Mouse Anti-MS4A1 Recombinant Antibody (clone 2H7) (CAT#: FAMAB-0241CQ)

Recombinant Mouse Antibody clone 2H7, which is specific to CD20. Mouse antibody 2H7 recognizes the CD20 cell surface phosphoprotein that is expressed in normal as well as malignant B cells. The antibody is highly effective in mediating antibody-dependent cellular cytotoxicity with human effector cells and complement-dependent cytotoxicity with human complement. The epitope has been mapped to the amino acid sequence YNCEPANPSEKNSPST, located in the large extracellular loop of CD20.


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Inhib

Figure 1 Inhibition of the binding of fluorescein isothiocyanate-lamouse 2H7 and chimeric 2H7 antibody as assayed by fluorescenceactivated cell sorter.

Figure 1 Inhibition of the binding of fluorescein isothiocyanate-lamouse 2H7 and chimeric 2H7 antibody as assayed by fluorescenceactivated cell sorter.

DHL-10 cells were incubated with the blocking antibodies before fluorescein isothiocyanate-mouse 2H7 (3 dml) was added.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b, κ
  • Specificity
  • CD20
  • Species Reactivity
  • Human, Non human primates
  • Clone
  • 2H7
  • Applications
  • ELISA, FC, IHC, IP

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 2H7"

See other products for "MS4A1"

Humanized Antibody

CAT Product Name Application Type
TAB-772 Human Anti-MS4A1 Recombinant Antibody (TAB-772) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1
TAB-771 Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) IF, IP, Neut, FuncS, ELISA, FC, ICC Humanized IgG1, κ
TAB-1638CL Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) ADCC, CDC Humanized IgG
TAB-1639CL Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) ADCC, CDC, Apop Humanized IgG
TAB-1640CL Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) ADCC, CDC, Apop, FuncS Humanized IgG

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-1633CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5) FC Chimeric antibody (mouse/human)
TAB-1634CL-S(P) Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5-DXL) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
TAB-1633CL-F(E) Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch1F5) FC Chimeric antibody (mouse/human)
TAB-1634CL-F(E) Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch1F5-DXL) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
TAB-1656CL-F(E) Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch2B8) FC, CMCD, ADCC, Activ, Inhib, Depletion Chimeric antibody (mouse/human)

Hyper-galactosylated

High-mannose Glycoform

CAT Product Name Application Type
Gly-155LC-1 Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-171LC Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) ELISA Chimeric antibody (mouse/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1751CQ Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) Neut, FuncS Mouse IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-772 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-016 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-028 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-207 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-771 Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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