Recombinant Anti-MS4A1 Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC222)

This biparatopic antibody (bpAb) is designed with tandem scFv arms for simultaneous, high-affinity binding to two distinct MS4A1 (CD20) epitopes: one located closer to the N-terminus of CD20, and a discontinuous epitope within the extracellular domain of CD20.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Mouse
  • Specificity
  • Human MS4A1
  • Species Reactivity
  • Human
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Epitope 1
  • An epitope located closer to the N-terminus of CD20
  • Epitope 2
  • A discontinuous epitope within the extracellular domain of CD20.
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, IF, WB
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Membrane Spanning 4-Domains A1

Target

  • Introduction
  • This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1;

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CAT Product Name Application Type
TAB-772 Human Anti-MS4A1 Recombinant Antibody (TAB-772) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1
TAB-771 Humanized Anti-MS4A1 Recombinant Antibody (TAB-771) IF, IP, Neut, FuncS, ELISA, FC, ICC Humanized IgG1, κ
TAB-133 Anti-Human CD20 Recombinant Antibody (Afutuzumab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG3 - kappa
TAB-1635CL Anti-Human MS4A1 Recombinant Antibody (BVX20) Inhib Humanized antibody
TAB-1636CL Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL) ADCC, CDC Humanized IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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