Mouse Anti-MSH6 Recombinant Antibody (clone 3A10H7)

Name: Mouse Anti-MSH6 Recombinant Antibody (clone 3A10H7)
SKU: VS3-QX789
Rating: 5 (1 reviews)

CAT#: VS3-QX789

This product is a mouse antibody that recognizes MSH6. The antibody can be used in applications: WB, IHC, ICC, FC, ELISA.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28376/if_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human lymph node

Immunohistochemical staining of human lymph node shows strong nuclear positivity in reaction center cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9091/ihc_selected.jpg

Subcellular Location and Protein Expression Figure 3 IHC staining of human colon

Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/ihc_selected.jpg

Subcellular Location and Protein Expression Figure 4 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, golgi apparatus & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28376/290_E8_2_red_green.jpg

Subcellular Location and Protein Expression Figure 5 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28376/249_E8_1_red_green.jpg

Normal Tissue Figure 6 Cerebral cortex

Glial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_B_8_5.jpg

Normal Tissue Figure 7 Colon

Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_7_3.jpg

Normal Tissue Figure 8 Liver

Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_9_4.jpg

Normal Tissue Figure 9 Kidney

Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_8_5.jpg

Normal Tissue Figure 10 Testis

Elongated or late spermatids
Staining:High
Intensity: Strong
Quantity:>75%
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Peritubular cells
Staining:High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining:High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining:High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining:High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_6_6.jpg

Normal Tissue Figure 11 Ovary

Ovarian stroma cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_4_7.jpg

Normal Tissue Figure 12 Lymph node

Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70870/151813_A_9_8.jpg

RNA Expression Figure 13 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000116062-MSH6

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Specifications

Immunogen
Purified recombinant fragment of MSH6 expressed in E. coli.

Host Species
Mouse

Derivation
Mouse

Type
Mouse IgG1

Specificity
MSH6

Species Reactivity
Human

Clone
3A10H7

Applications
WB, IHC, ICC, FC, ELISA

Conjugate
Unconjugated

Product Property

Clonality
Monoclonal

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Storage
Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping
Ice packs

Applications

Application Notes
WB: 1:500-1:2000; ELISA: 1:10000

Target

Alternative Names
GTBP; GTMBP; HNPCC5; HSAP; p160

Gene ID
2956

UniProt ID
P52701

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS3-QX789.pdf

MSDS

MSDS - VS3-QX789.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

CAT
Product Name

Secondary Antibody

CAT
Product Name

See other products for "MSH6"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
DrMAB-407	Recombinant Human Anti-Human MSH6 Antibody Fab Fragment, clone D205	IP, IF, ELISA, IP-MS	Fab

CAT	Product Name	Application	Type
MOB-1179CT	Recombinant Mouse anti-Human MSH6 Monoclonal antibody (4B20I8)	ELISA, IHC-P, WB
MRO-2045-CN	Rabbit Anti-MSH6 Polyclonal Antibody (MRO-2045-CN)	WB, IF, IHC, FC	Rabbit IgG
VS3-QX788	Mouse Anti-MSH6 Recombinant Antibody (clone 3H9-G10-D10)	WB, IHC, ICC, FC, ELISA	Mouse IgG1
VS3-FY960	Recombinant Mouse Anti-MSH6 Antibody (clone 1D1C2)	ELISA, WB, FC	Mouse IgG1
VS3-FY961	Recombinant Mouse Anti-MSH6 Antibody (clone 2E3A10)	ELISA, WB, IHC, FC	Mouse IgG2b

CAT	Product Name	Application	Type
MOR-2299	Hi-Affi™ Recombinant Rabbit Anti-MSH6 Monoclonal Antibody (DS2299AB)	ICC, IF, IHC-P, IP, WB	IgG

CAT	Product Name	Application	Type
VS-0424-XY189	AbPlus™ Anti-MSH6 Magnetic Beads (JA84-26)	IP, Protein Purification

CAT	Product Name	Application
VS-0325-XY1376	Anti-MSH6 Immunohistochemistry Kit	IHC
VS-0525-XY4525	Anti-Mouse MSH6 Immunohistochemistry Kit	IHC
VS-0525-XY4524	Anti-Human MSH6 Immunohistochemistry Kit	IHC
VS-0525-XY4527	Anti-Rat MSH6 Immunohistochemistry Kit	IHC

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