Mouse Anti-MST1R Monoclonal Antibody (VS7-0425-WR429)

Name: Mouse Anti-MST1R Monoclonal Antibody (VS7-0425-WR429)
SKU: VS7-0425-WR429
Rating: 5 (1 reviews)

CAT#: VS7-0425-WR429

This product is a mouse IgG antibody that binds to human MST1R. The antibody recognizes specific amino acid domain of human Ron (aa210-320). It can be used for WB and ELISA assays.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/44_E6_1_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_5.jpg

Normal Tissue Figure 3 Colon

Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_3.jpg

Normal Tissue Figure 4 Liver

Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_9_5.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_6_6.jpg

Normal Tissue Figure 7 Skin

Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_1.jpg

Normal Tissue Figure 8 Lymph node

Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_8_8.jpg

RNA Expression Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164078-MST1R

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Specifications

Immunogen
Recombinant human Ron (aa210-320) fragment expressed in E. Coli.

Host Species
Mouse

Type
Mouse IgG

Specificity
Human MST1R

Species Reactivity
Human

Molecule Class
Met Family

Applications
WB, ELISA

Conjugate
Unconjugated

Related Disease
Nasopharyngeal carcinoma, 3 (NPCA3)

Product Property

Clonality
Monoclonal

Purity
>95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid

Format
Liquid

Concentration
1 mg/ml

Preservative
0.03% sodium azide

Storage
Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Shipping
Ice packs

Applications

Application Notes
Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000

Target

Alternative Names
MST1R; Macrophage Stimulating 1 Receptor; Soluble RON Variant 2; Soluble RON Variant 1; MST1R Variant RON62; CDw136; MSP Receptor; Soluble RON Variant 3; RON Variant E2E3; PTK8 Protein Tyrosine Kinase 8; RON; PTK8; CD136; P185-Ron; MST1R Variant RON30; Ma

Gene ID
4486

UniProt ID
Q04912

Long Name
Macrophage Stimulating 1 Receptor

Cellular Localization
Membrane

Post Translation Modifications
Cleavage on pair of basic residues; Disulfide bond; Glycoprotein; Phosphoprotein; Ubl conjugation

Protein Refseq
NP_001231866.1

Function
Kinase; Receptor; Transferase; Tyrosine-protein kinase

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS7-0425-WR429.pdf

MSDS

MSDS - VS7-0425-WR429.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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