Mouse Anti-MST1R Recombinant Antibody (clone 07F01) (CAT#: HPAB-687-FY)
This product is a recombinant antibody that recognizes MST1R. The monoclonal antibody 07F01 reacts with the epitope of MST1R. antibody 07F01 inhibits MSP induced ERK phosphorylation in T47D cells. This antibody can be used to treat certain forms of cancer that are associated with activation of RON.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Neut
Figure 1 Anti-RON antibodies potently inhibit MSP binding to RON.
Neutralization of ligand binding.
Inhib
Figure 2 Anti-RON antibodies potently inhibit MSP binding to RON.
Anti-RON antibodies inhibit MSP-induced signaling in T47D Cells.
Inhib
Figure 3 Anti-RON mAbs inhibit RON receptor-driven tumorigenesis.
Proprietary Directed Complemented (DC) breast tumor model driven by WT RON.
Cyt
Figure 4 07F01 decreases proliferation (Ki67) and increases apoptosis (TUNEL) in WT RON DC tumors.
ELISA
Figure 5 Pharmacokinetic parameters of 29B06 and 07F01.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MST1R
- Species Reactivity
- Human
- Clone
- 07F01
- Applications
- Neut, Inhib, Cyt, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The MST1R antibody has been reported in applications of Neutralization, Inhibition, Cytotoxicity, Enzyme-linked Immunosorbent Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3123z | Mouse Anti-MST1R Recombinant Antibody (clone 29B12) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-J0189-YC | Mouse Anti-MST1R Recombinant Antibody (clone 17F06) | Neut, ELISA, FuncS, Inhib | Mouse IgG2a, λ |
| HPAB-J0190-YC | Human Anti-MST1R Recombinant Antibody (clone Ch07F01 C102S) | ELISA, Neut, FuncS | Chimeric (mouse/human) IgG1, κ |
| HPAB-J0191-YC | Human Anti-MST1R Recombinant Antibody (clone Sh07F01 Hv3-48) | ELISA, Neut, FuncS | Humanized (mouse/human) IgG |
| VS3-XY1116 | Mouse Anti-MST1R Recombinant Antibody (clone 1B5A9) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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