Mouse Anti-MST1R Recombinant Antibody (clone 07F01)

CAT#: HPAB-687-FY

This product is a recombinant antibody that recognizes MST1R. The monoclonal antibody 07F01 reacts with the epitope of MST1R. antibody 07F01 inhibits MSP induced ERK phosphorylation in T47D cells. This antibody can be used to treat certain forms of cancer that are associated with activation of RON.

Published Data Gene Expression
Figure 1 Anti-RON antibodies potently inhibit MSP binding to RON. Figure 2 Anti-RON antibodies potently inhibit MSP binding to RON. Figure 3 Anti-RON mAbs inhibit RON receptor-driven tumorigenesis. Figure 4 07F01 decreases proliferation (Ki67) and increases apoptosis (TUNEL) in WT RON DC tumors. Figure 5 Pharmacokinetic parameters of 29B06 and 07F01.
Figure 1 IF staining of human cell line U-2 OS Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Liver Figure 5 Kidney Figure 6 Testis Figure 7 Skin Figure 8 Lymph node Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human MST1R
  • Species Reactivity
  • Human
  • Clone
  • 07F01

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The MST1R antibody has been reported in applications of Neutralization, Inhibition, Cytotoxicity, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • RON; PTK8; CD136; NPCA3; CDw136
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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