Mouse Anti-MST1R Recombinant Antibody (clone 29B06) (CAT#: HPAB-688-FY)
This product is a recombinant antibody that recognizes MST1R. The monoclonal antibody 18H09 reacts with the epitope of MST1R. The antibody 18H09 inhibits or reduces the proliferation of a tumor cell by inhibiting the binding of human RON to its ligand, MSP.
Specific Inquiry
Neut
Figure 1 Anti-RON antibodies potently inhibit MSP binding to RON.
Neutralization of ligand binding.
Inhib
Figure 2 29B06 is efficacious in human cancer xenograft.
29B06 dose response with H358 xenografts.
Inhib
Figure 3 Anti-RON mAbs inhibit RON receptor-driven tumorigenesis.
Proprietary Directed Complemented (DC) breast tumor model driven by RON160.
ELISA
Figure 4 Pharmacokinetic parameters of 29B06 and 07F01.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MST1R
- Species Reactivity
- Human
- Clone
- 29B06
- Applications
- Neut, Inhib, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The MST1R antibody has been reported in applications of Neutralization, Inhibition, Enzyme-linked Immunosorbent Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-184 | Anti-Human RON Recombinant Antibody (Narnatumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - kappa |
| TAB-332CT-S(P) | Anti-Human RON Recombinant Antibody scFv Fragment (TAB-332CT-S(P)) | WB, ELISA, FC | Human antibody |
| TAB-333CT-S(P) | Human Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-333CT-S(P)) | WB, ELISA, FC, IP | Human scFv |
| TAB-332CT-F(E) | Anti-Human RON Recombinant Antibody Fab Fragment (TAB-332CT-F(E)) | WB, ELISA, FC | Human antibody |
| TAB-333CT-F(E) | Human Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-333CT-F(E)) | WB, ELISA, FC, IP | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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