Human Anti-MSTN Recombinant Antibody (clone 10B3-H2L2); Fab Fragment (CAT#: HPAB-0777-CN-F(E))
This product is a humanized antibody that binds to myostatin. The 10B3-H2L2 is the humanized version of murine antibody 10B3. H2L2 inhibit the myostatin-induced activation of cell signalling, resulting in luciferase expression in A204 cells.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human skeletal muscle
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
Figure 2 RNA cell line category: Group enriched (LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human MSTN
- Species Reactivity
- Human
- Clone
- 10B3-H2L2
- Applications
- ELISA
- Related Disease
- Diseases associated with anyone or a combination of decreased muscle mass, muscle strength, muscle function
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Myostatin; GDF8; Growth Differentiation Factor 8; Growth/Differentiation Factor 8; MSLHP; GDF-8;
- Gene ID
- 2660
- UniProt ID
- O14793
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2313z | Mouse Anti-MSTN Recombinant Antibody (clone 19F12) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2b |
| HPAB-0013-FY | Mouse Anti-MSTN Recombinant Antibody (clone H8L5) | ELISA | Mouse IgG1 |
| HPAB-0025-FY | Human Anti-MSTN Recombinant Antibody (HPAB-0025-FY) | FC, SPR, FuncS | Human IgG |
| HPAB-0026-FY | Human Anti-MSTN Recombinant Antibody (HPAB-0026-FY) | FuncS | Human IgG |
| HPAB-0268CQ | Mouse Anti-MSTN Recombinant Antibody (HPAB-0268CQ) | ELISA, Neut, FuncS | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
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