Human Anti-MUC1 Recombinant Antibody (clone MB5)
CAT#: VS-0724-XY87
This is a recombinant human antibody that recognizes human MUC1 (Mucin 1, cell surface associated), which is a membrane-bound protein. The antibody has high affinity against human MUC1 and the KD value is 401 nM. It has been repored for use in Enzyme-linked Immunosorbent Assay.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line RPTEC TERT1
Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/1789_B9_13_cr596f381e20667_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1986/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/100_E7_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/101_E7_1_blue_red_green.jpg
Normal Tissue
Figure 5 Stomach
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_2_1.jpg
Normal Tissue
Figure 6 Colon
Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_9_3.jpg
Normal Tissue
Figure 7 Kidney
Collecting ducts
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_8_5.jpg
Normal Tissue
Figure 8 Testis
Elongated or late spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_6_6.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (CAPAN-2, OE19, RPTEC TERT1, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185499-MUC1
❮
❯
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- MUC1
- Species Reactivity
- Human
- Clone
- MB5
- Applications
- ELISA, SPR
- Related Disease
- Tubulointerstitial Kidney Disease; Autosomal Dominant, 2
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- SPR: The KD value of MB5 agaisnt MUC1 is 401 nM.
Target
- Alternative Names
- EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADTKD2; Ca15-3; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC
- Gene ID
- 4582
- UniProt ID
- P15941
- Cellular Localization
- Apical cell membrane
- Post Translation Modifications
- Glycosylation at Asn1055, Asn1133, Thr131, Thr139, Ser140, Thr144, Asn957, Asn975, Ser989, Thr990, Ser993, Ser999, Thr1001, Thr1003, Thr1004, Ser1009, Thr1010, and Asn1029.
- Protein Refseq
- NP_001018016.1; NP_001018017.1; NP_001037855.1
- Function
- The alpha subunit has cell adhesive properties.
Can act both as an adhesion and an anti-adhesion protein.
May provide a protective layer on epithelial cells against bacterial and enzyme attack.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2049-VHH | Recombinant Anti-human MUC1 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| HPAB-AP504-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP504-YC) | FC | Camel VHH |
| HPAB-AP505-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP505-YC) | ELISA | Camel VHH |
| HPAB-0736-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0736-YJ-VHH) | ELISA | Camelid VHH |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-173 | Anti-Human MUC1 Recombinant Antibody (TAB-173) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| TAB-H65 | Anti-Human MUC1 Recombinant Antibody (Sontuzumab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 |
| TAB-413MZ-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-413MZ-F(E)) | ELISA | Humanized Fab |
| TAB-425MZ-F(E) | Anti-Human MUC1 Recombinant Antibody Fab Fragment (huDMB5F3) | FC | Humanized antibody |
| TAB-430MZ-F(E) | Anti-Human MUC1 Recombinant Antibody Fab Fragment (BLC595) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L036E | anti-MUC1 immunotoxin C242 (Fab)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L064E | anti-MUC1 immunotoxin H23 (scFv)-PE | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-656 | Mouse Anti-MUC1 Recombinant Antibody; scFv Fragment | WB, IF, FuncS | Mouse scFv |
| HPAB-0091-YC-S(P) | Mouse Anti-MUC1 Recombinant Antibody; scFv Fragment (HPAB-0091-YC-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-0094-YC-S(P) | Mouse Anti-MUC1 Recombinant Antibody (clone 12D10); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0670-CN-S(P) | Human Anti-MUC1 Recombinant Antibody; scFv Fragment (HPAB-0670-CN-S(P)) | FC | Human scFv |
| HPAB-AP738-YC-S(P) | Mouse Anti-MUC1 Recombinant Antibody; scFv Fragment (HPAB-AP738-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0388CL-F(E) | Mouse Anti-Human MUC1 Recombinant Antibody Fab Fragment | WB, IHC | |
| TAB-411MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-411MZ-F(E)) | ELISA | Mouse Fab |
| TAB-416MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-416MZ-F(E)) | IF | Mouse Fab |
| TAB-417MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-417MZ-F(E)) | IF | Mouse Fab |
| TAB-418MZ-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-418MZ-F(E)) | ELISA, SDS-PAGE, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-412MZ | Human Anti-MUC1 Recombinant Antibody (TAB-412MZ) | ELISA | Chimeric (mouse/human) IgG |
| TAB-412MZ-S(P) | Mouse Anti-MUC1 Recombinant Antibody; scFv Fragment (TAB-412MZ-S(P)) | ELISA | Mouse scFv |
| TAB-412MZ-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-412MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-431MZ | Anti-Human MUC1 Recombinant Antibody (PH1) | ELISA, WB, FC, IHC, SPR | Human antibody |
| TAB-432MZ | Human Anti-MUC1 Recombinant Antibody (TAB-432MZ) | ELISA, FC, FACS, DB, SPR | Human IgG |
| TAB-433MZ | Human Anti-MUC1 Recombinant Antibody (TAB-433MZ) | ELISA, FC, FACS, DB, SPR | Human IgG |
| TAB-434MZ | Human Anti-MUC1 Recombinant Antibody (TAB-434MZ) | ELISA, FC, FACS, DB, SPR | Human IgG |
| TAB-431MZ-F(E) | Anti-Human MUC1 Recombinant Antibody Fab Fragment (PH1) | ELISA, WB, FC, IHC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-012LC | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) | ELISA, FC, IHC | Humanized antibody |
| Gly-120LC | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-012LC-1 | Recombinant Anti-Human MUC1 Antibody (Fab glycosylation/Sialylated) | ELISA, FC, IHC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-109LC | Recombinant Anti-Human MUC1 Antibody (Fc glycosylation) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-121LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| Gly-122LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| Gly-124LC | Recombinant Anti-Human MUC1 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0364MZ | Recombinant Mouse Anti-Human Mucin 1, Cell Surface Associated, FITC-Conjugated Antibody (clone Cer-EP5) | ELISA | Mouse antibody |
| PABC-399 | Mouse Anti-MUC1 Recombinant Antibody (clone AR20.5) | ELISA, FC, FuncS | Mouse IgG1 |
| PABC-400 | Mouse Anti-MUC1 Recombinant Antibody (clone SM3) | FC, IHC-Fr, IF, ELISA, IHC-P | Mouse IgG1 |
| HPAB-0495-FY | Human Anti-MUC1 Recombinant Antibody (HPAB-0495-FY) | ELISA, WB, IP | Human IgE |
| HPAB-0496-FY | Human Anti-MUC1 Recombinant Antibody (HPAB-0496-FY) | ELISA, IHC | Human IgE |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0379MZ | Chicken Anti-MUC1 Polyclonal IgY | IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2320 | Hi-Affi™ Recombinant Rabbit Anti-MUC1 Monoclonal Antibody (DS2320AB) | IHC-P, IHC-Fr | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0838LC | Recombinant Mouse Anti-Human MUC1 Antibody (SM3) | ELISA | IgG1 |
| EPAF-0581CQ | Recombinant Mouse Anti-Human MUC1 Antibody (B27.29) | Neut, FC | IgG1 |
| EPAF-0583CQ | Recombinant Mouse Anti-Human MUC1 Antibody (BC4E549) | Neut, FC | IgG1 |
| EPAF-0584CQ | Recombinant Mouse Anti-Human MUC1 Antibody (DF3) | Neut, FC | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0225-YC-F(E) | Mouse Anti-MUC1 Recombinant Antibody (clone MUSE11); Fab Fragment | IHC | Mouse Fab |
| HPAB-0272CQ-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0272CQ-F(E)) | ELISA, FC, FuncS | Human Fab |
| HPAB-0872LY-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0872LY-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0873LY-F(E) | Human Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0873LY-F(E)) | ELISA, WB, FC | Humanized Fab |
| HPAB-0874LY-F(E) | Mouse Anti-MUC1 Recombinant Antibody; Fab Fragment (HPAB-0874LY-F(E)) | ELISA, WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H56 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H56) | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-H65 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H65) | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-026ML | Afuco™ Anti-MUC1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-026ML) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-166 | Afuco™ Anti-MUC1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-166) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-H77 | Afuco™ Human Anti-MUC1 Recombinant Antibody, ADCC Enhanced (AFC-TAB-H77) | ELISA, FC, IP, FuncS, IF | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP745-YC | Mouse Anti-MUC1 Recombinant Antibody (HPAB-AP745-YC) | ELISA | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY192 | AbPlus™ Anti-MUC1 Magnetic Beads (139H2) | IP, Protein Purification | |
| VS-0724-YC1494 | AbPlus™ Anti-MUC1 Magnetic Beads (VS-0724-YC1494) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY26 | Human Anti-MUC1 (clone 1B2) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY169 | CytoStream™ Mouse Anti-MUC1 Recombinant Antibody (VS-0225-XY169) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1394 | Anti-MUC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4575 | Anti-Human MUC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4576 | Anti-Mouse MUC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC379 | Recombinant Anti-MUC1 Vesicular Antibody, EV Displayed (VS-0425-YC379) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC131 | Recombinant Anti-MUC1 Biparatopic Antibody, Tandem scFv | ELISA, IHC | Tandem scFv |
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