Afuco™ Anti-MUC5AC ADCC Recombinant Antibody (Ensituximab), ADCC Enhanced (CAT#: AFC-TAB-200)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to 5AC. Ensituximab is a chimeric monoclonal antibody used in the treatment of cancers.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in stomach 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_6_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_6_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_9_4_val_selected.jpg
Figure 3 Stomach
(Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_3_1.jpg
(Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_3_1.jpg
Figure 4 RNA cell line category: Group enriched (A549, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215182-MUC5AC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215182-MUC5AC
Specifications
- Immunogen
- M1 mucin preparation from the fluid of an ovarian mucinous cyst.
- Host Species
- Chimeric
- Derivation
- Chimeric (mouse/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Ensituximab
- Applications
- IP, IF, FuncS, FC, Neut, ELISA
- Conjugate
- Unconjugated
- Generic Name
- Ensituximab
- Related Disease
- Colorectal cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Ensituximab; 1092658-06-4; NPC-1C; NEO-101; MUC5AC; mucin 5AC, oligomeric mucus/gel-forming; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin-5AC; MUC5; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen
- Gene ID
- 4586
- UniProt ID
- P98088
Related Resources
Please refer to Ensituximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ensituximab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Ensituximab"
Anti-Human MUC5AC Recombinant Antibody (Ensituximab)Recombinant monoclonal antibody to 5AC. Ensituximab is a chimeric monoclonal antibody used in the treatment of cancers.
See other products for "Clone Ensituximab"
See other products for "MUC5AC"
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-200 | Anti-Human MUC5AC Recombinant Antibody (Ensituximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-404MZ | Mouse Anti-MUC5AC Recombinant Antibody (TAB-404MZ) | ELISA, Inhib, IHC, IA | Mouse IgG |
| TAB-404MZ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-404MZ-S(P)) | IHC | Mouse scFv |
| TAB-404MZ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-404MZ-F(E)) | IHC | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-405MZ | Human Anti-MUC5AC Recombinant Antibody (TAB-405MZ) | IF, WB, IHC, IA | Humanized IgG |
| TAB-405MZ-S(P) | Human Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-405MZ-S(P)) | IHC | Humanized scFv |
| TAB-406MZ-S(P) | Anti-Human MUC5AC Recombinant Antibody scFv Fragment (VH-1) | FC, ELISA | Humanized antibody |
| TAB-405MZ-F(E) | Human Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-405MZ-F(E)) | IHC | Humanized Fab |
| TAB-406MZ-F(E) | Anti-Human MUC5AC Recombinant Antibody Fab Fragment (VH-1) | FC, ELISA | Humanized antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1265CT | Recombinant Mouse anti-Human MUC5AC Monoclonal antibody (2-24N2) | ELISA, ICC, IHC-Fr, IHC-P, WB | |
| HPAB-AP150-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1) | ELISA, Cyt | Human IgG |
| HPAB-AP151-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10) | ELISA, Cyt | Human IgG |
| HPAB-0566-YJ | Mouse Anti-MUC5AC Recombinant Antibody (HPAB-0566-YJ) | WB, IHC, ELISA | Mouse IgG1 |
| VS3-WK822 | Mouse Anti-MUC5AC Recombinant Antibody (VS3-WK822) | IHC | Mouse IgG1 |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0585CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (19-O Le) | ELISA | IgM |
| EPAF-0586CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (2-25 Le) | ELISA | IgG1 |
| EPAF-0587CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (7 Le) | ELISA | IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-S(P) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); scfv Fragment | ELISA | Mouse scfv |
| HPAB-AP150-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-AP151-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-0566-YJ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (HPAB-0566-YJ-S(P)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-F(E) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); Fab Fragment | ELISA | Mouse Fab |
| HPAB-AP150-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-AP151-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-0566-YJ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (HPAB-0566-YJ-F(E)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse Fab |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1061 | PE-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1062 | APC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1063 | FITC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1064 | B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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