AbPlus™ Anti-MYC Magnetic Beads (33)
CAT#: VS-0424-XY194
The AbPlus Anti-MYC Magnetic Beads (33) is an innovative affinity resin which is bound with anti-MYC specific antibody (33). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MYC protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55893/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66556/1279_E11_3_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows moderate nucleolar positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55893/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human rectum
Immunohistochemical staining of human rectum shows moderate nuclear and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/84/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 5 IHC staining of human caudate
Immunohistochemical staining of human caudate shows distinct nucleolar positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 6 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55893/883_H10_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 7 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55893/879_G9_1_red_green.jpg
Normal Tissue
Figure 8 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/30810_B_7_5.jpg
Normal Tissue
Figure 9 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/30810_A_9_4.jpg
Normal Tissue
Figure 10 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/30810_A_7_5.jpg
Normal Tissue
Figure 11 Cervix
Squamous epithelial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/30810_B_8_3.jpg
Normal Tissue
Figure 12 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10307/30810_A_9_8.jpg
RNA Expression
Figure 13 RNA cell line category: Cell line enhanced (RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136997-MYC
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-MYC specific antibody (33)
- Target
- MYC
- Target Species
- Human, Mouse, Avian
- Antibody Clone
- 33
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
- Alternative Names
- MYC Proto-Oncogene, BHLH Transcription Factor; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Transcription Factor P64; Proto-Oncogene C-Myc; BHLHe39; Myc-Related Translation/Localization Regulatory Factor
- Gene ID
- 4609
- UniProt ID
- P01106
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Related Signaling Pathways
BCR Signaling Pathway
Related Diseases
Bladder Cancer
Breast Cancer
Colorectal Cancer
Gastric Cancer
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MYC"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-281 | Mouse Anti-MYC Recombinant Antibody (clone 9E10) | WB, IHC, FuncS | Mouse IgG |
| MOB-0268CT | Recombinant Mouse anti-Human MYC Monoclonal antibody (4H40) | ELISA, ICC, IF, IHC-P, IP, WB | |
| FAMAB-0112-CN | Mouse Anti-MYC Recombinant Antibody (clone CT14) | ELISA, WB, FC, Inhib | Mouse IgG2a |
| MRO-1778-CN | Rabbit Anti-MYC Polyclonal Antibody (MRO-1778-CN) | WB | Rabbit IgG |
| MRO-1779-CN | Rabbit Anti-MYC Polyclonal Antibody (MRO-1779-CN) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-281 | Mouse Anti-MYC Recombinant Antibody (clone 9E10); scFv Fragment | WB, IHC, FuncS | Mouse scFv |
| FAMAB-0112-CN-S(P) | Mouse Anti-MYC Recombinant Antibody (clone CT14); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-281 | Mouse Anti-MYC Recombinant Antibody (clone 9E10); Fab Fragment | WB, IHC, FuncS | Mouse Fab |
| FAMAB-0112-CN-F(E) | Mouse Anti-MYC Recombinant Antibody (clone CT14); Fab Fragment | ELISA, WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0400MC | Anti-c-Myc antibody (HRP) | ELISA, IHC-P, IHC-Fr, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0380MZ | Chicken Anti-c-Myc (ab1) Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| BRD-0381MZ | Chicken Anti-c-Myc (ab2) Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2336 | Hi-Affi™ Recombinant Rabbit Anti-MYC Monoclonal Antibody (DS2336AB) | WB, IP, ICC | IgG |
| MOR-4554 | Hi-Affi™ Recombinant Rabbit Anti-MYC Monoclonal Antibody (TH64DS) | WB, IF, ICC, FC | IgG |
| MOR-0050-FY | Rabbit Anti-MYC Recombinant Antibody (clone AFY0021) | ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY133 | Mouse Anti-NHP MYC Recombinant Antibody (clone MYC699) | IF, FC, ELISA | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4607 | Anti-MYC Immunohistochemistry Kit | IHC | |
| VS-0525-XY4608 | Anti-Human MYC Immunohistochemistry Kit | IHC | |
| VS-0525-XY4609 | Anti-Mouse MYC Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC263 | SmartAb™ Recombinant Anti-MYC pH-dependent Antibody (Clone CT14) | ELISA, WB, FC, Inhib | Mouse IgG2a |
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