AbPlus™ Anti-MYD88 Magnetic Beads (VS-0724-YC155)
CAT#: VS-0724-YC155
The AbPlus Anti-MYD88 Magnetic Beads (VS-0724-YC155) is an innovative affinity resin which is bound with anti-MYD88 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MYD88 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/956_E1_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9104/33507_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (SK-BR-3)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172936-MYD88
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-MYD88 specific antibody
- Target
- MYD88
- Immunogen
- Recombinant human MYD88 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
- Alternative Names
- Myeloid Differentiation Primary Response 88; Myeloid Differentiation Primary Response Gene (88); Myeloid Differentiation Primary Response Protein MyD88; Mutant Myeloid Differentiation Primary Response 88; MYD88D;
- Gene ID
- 4615
- UniProt ID
- Q99836
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Related Signaling Pathways
TLR Signaling Pathway
Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MYD88"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2312z | Mouse Anti-MYD88 Recombinant Antibody (clone 15G2) | WB, FC, ICC, IF | Mouse IgG2a |
| MOB-2400CT | Recombinant Mouse anti-Human MYD88 Monoclonal antibody (FQS6600) | WB, ICC, IF, IHC-P | |
| MRO-1050-CN | Recombinant Rabbit Anti-MYD88 Monoclonal Antibody (CBACN-389) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK1125 | Rabbit Anti-MYD88 Recombinant Antibody (VS3-WK1125) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| VS3-WK1601 | Mouse Anti-MYD88 Recombinant Antibody (clone 2H12) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2337 | Hi-Affi™ Recombinant Rabbit Anti-MYD88 Monoclonal Antibody (DS2337AB) | WB, IHC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY332 | Mouse Anti-NHP MYD88 Recombinant Antibody (clone 4D6) | WB, ICC, FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1403 | Anti-MYD88 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4612 | Anti-Human MYD88 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC755 | CytoStream™ Rabbit Anti-MYD88 Recombinant Antibody (VS13-YC755) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
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