AbPlus™ Anti-MYH7 Magnetic Beads (VS-0724-YC559) (CAT#: VS-0724-YC559)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-MYH7 specific antibody

• Target
• MYH7

• Immunogen
• Recombinant human MYH7 fragment derived from E. coli.

• Target Species
• Human, Cynomolgus

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008]

• Alternative Names
• Myosin Heavy Chain 7; Myosin, Heavy Polypeptide 7, Cardiac Muscle, Beta; Myosin Heavy Chain, Cardiac Muscle Beta Isoform; Myosin Heavy Chain Slow Isoform; Myopathy, Distal 1; MyHC-Beta; Myhc-Slow; MYHCB; Myosin, Heavy Chain 7, Cardiac Muscle, Beta; Cardiac Muscle Myosin Heavy Chain 7 Beta;

• Gene ID
• 4625

• UniProt ID
• P12883

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