Mouse Anti-MYO18B Recombinant Antibody (VS3-FY2816) (CAT#: VS3-FY2816)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human MYO18B

• Species Reactivity
• Human

• Applications
• Western Blot, Immunohistochemistry, Flow cytometry

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 285.2 kDa.

• Related Disease
• Klippel-Feil Syndrome 4, Autosomal Recessive, With Nemaline Myopathy And Facial Dysmorphism and Klippel-Feil Syndrome

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Immunohistochemistry: 1/50-1/200
  Flow cytometry: 1/10-1/25

• Alternative Names
• Myosin XVIIIB; Unconventional Myosin-XVIIIb; Myosin 18B; KFS4

• Gene ID
• 84700

• UniProt ID
• Q8IUG5

• Sequence Similarities
• Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

• Cellular Localization
• Cytoplasm
  Nucleus
  Cytoplasm, myofibril, sarcomere

• Post Translation Modifications
• Modification sites at PhosphoSitePlus (Q8IUG5)
  Modification sites at neXtProt (NX_Q8IUG5)
  Glycosylation from GlyGen (Q8IUG5) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• XP_011528761.1; XP_011528762.1; XP_011528763.1; XP_011528766.1

• Function
• May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes.
  May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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