Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 208,D-5) (CAT#: FAMAB-0234JF)
Recombinant monoclonal antibody specially binds to Neisseria meningitidis PorA P1.7. This mouse human anti-p1.7 antibody (208,D-5) can be useful to study the protective effects against meningococcal disease.
Specific Inquiry
WB
Figure 1 Overproduction of Omp85, Hsf, TbpA, and NspA.
Impact on the content of proteins in MenB OMVs.
Weynants, V. E., Feron, C. M., Goraj, K. K., Bos, M. P., Denoël, P. A., Verlant, V. G., ... & Poolman, J. T. (2007). Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis. Infection and immunity, 75(11), 5434-5442.
ELISA
Figure 2 Bactericidal activity against N. meningitidis strains of serum antibodies from mice immunized with OMV vaccines.
The data are the means of three different mixing experiments performed using the same serum samples and are expressed as the reciprocal bactericidal titers.
Weynants, V. E., Feron, C. M., Goraj, K. K., Bos, M. P., Denoël, P. A., Verlant, V. G., ... & Poolman, J. T. (2007). Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis. Infection and immunity, 75(11), 5434-5442.
IHC
Figure 3 Expression of PorA-Soc fusion protein and its display on T4 phage.
Soc phage after treatment first with the loop 4-specific monoclonal antibody and then with the gold-conjugated anti-mouse second antibody.
Jiang, J., Abu-Shilbayeh, L. A. R. A., & Rao, V. B. (1997). Display of a PorA peptide from Neisseria meningitidis on the bacteriophage T4 capsid surface. Infection and immunity, 65(11), 4770-4777.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Neisseria meningitidis PorA P1.7
- Species Reactivity
- N. meningitidis
- Clone
- 208,D-5
- Applications
- WB, ELISA, IHC
- Related Disease
- Meningitis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The N. meningitidis porA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0234JF-F(E) | Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 208,D-5); Fab Fragment | FC, ELISA, FuncS | Mouse Fab |
| FAMAB-0235JF-F(E) | Human Anti-N. meningitidis porA Recombinant Antibody (clone 208,D-5-chIgG1); Fab Fragment | FC, ELISA, FuncS | Human Fab |
| FAMAB-0238JF-F(E) | Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 151,F-9); Fab Fragment | FC, ELISA, FuncS | Mouse Fab |
| FAMAB-0239JF-F(E) | Human Anti-N. meningitidis porA Recombinant Antibody (clone 151,F-9-chIgG1); Fab Fragment | FC, ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0234JF-S(P) | Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 208,D-5); scFv Fragment | FC, ELISA, FuncS | Mouse scFv |
| FAMAB-0238JF-S(P) | Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 151,F-9); scFv Fragment | FC, ELISA, FuncS | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0235JF | Human Anti-N. meningitidis porA Recombinant Antibody (clone 208,D-5-chIgG1) | FC, ELISA, FuncS | Chimeric (mouse/human) IgG1 |
| FAMAB-0238JF | Mouse Anti-N. meningitidis porA Recombinant Antibody (clone 151,F-9) | WB, ELISA, IHC, FC | Mouse IgG |
| FAMAB-0239JF | Human Anti-N. meningitidis porA Recombinant Antibody (clone 151,F-9-chIgG1) | FC, ELISA, FuncS | Chimeric (mouse/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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