Anti-NCAM2 (clone W24V113) Recombinant Antibody Coupled Liposome (VS-1024-FY115) (CAT#: VS-1024-FY115)
Antibody-conjugated liposomes against NCAM2 have shown significant potential in glioma research. First, they can precisely target glioma cells, enhancing the specificity and efficacy of the treatment. Additionally, the drug delivery system of liposomes can improve the bioavailability of anti-tumor drugs and reduce side effects. Moreover, this targeted approach is expected to enhance the effectiveness of immunotherapy, providing new treatment options for glioma patients.

(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nuclear bodies & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30901/1656_F1_5_selected.jpg

(Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30900/163375_B_8_5.jpg

(Endocrine cells Staining: Low Intensity: Weak Enterocytes - Microvilli Staining: Medium Intensity: Moderate Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30900/163375_A_7_3.jpg

(Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30900/163375_A_6_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154654-NCAM2
Specifications
- Potential Clinical Applications
- Glioma
Product Composition
- Clone
- W24V113
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This product is a recombinant mouse monoclonal antibody that has been engineered to specifically recognize and bind to human NCAM2. It is designed to facilitate various research applications, including studies on cell adhesion and neural development, where NCAM2 plays a crucial role. By utilizing this antibody, researchers can achieve more precise results in their experiments, leading to a better understanding of NCAM2's functions and its implications in human health and disease.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- NCAM2
- Introduction
- The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
- Alternative Names
- Neural Cell Adhesion Molecule 2; N-CAM-2; NCAM-2; NCAM21
- Full Name
- Neural Cell Adhesion Molecule 2
- Gene ID
- 4685
- UniProt ID
- O15394
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn177, Asn219, Asn309, Asn406, Asn419, Asn445, Asn474, and Asn562 ( NX_O15394 [NX_O15394-1] )
Modification sites at PhosphoSitePlus ( O15394 )
Glycosylation from GlyConnect NCAM2_HUMAN (1546)
Glycosylation from GlyGen (O15394) 11 sites, 15 N-linked glycans (4 sites)
- Protein Refseq
- XP_011527877.1; XP_011527882.1; XP_011527883.1; XP_011527884.1; XP_011527887.1
- Function
- May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NCAM2"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2373 | Hi-Affi™ Recombinant Rabbit Anti-NCAM2 Monoclonal Antibody (DS2373AB) | WB, IHC-P, ICC/IF, IP | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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