AbPlus™ Anti-NCF2 Magnetic Beads (VS-0724-YC707) (CAT#: VS-0724-YC707)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-NCF2 specific antibody

• Target
• NCF2

• Immunogen
• Recombinant human NCF2/NCF-2/P67phox, aa 1-526.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

• Alternative Names
• Neutrophil Cytosolic Factor 2; NADPH Oxidase Activator 2; Neutrophil Cytosolic Factor 2 (65kD, Chronic Granulomatous Disease, Autosomal 2); Chronic Granulomatous Disease, Autosomal 2; Neutrophil NADPH Oxidase Factor 2; 7 KDa Neutrophil Oxidase Factor;

• Gene ID
• 4688

• UniProt ID
• P19878

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