Rabbit Anti-NDUFB10 Recombinant Antibody (clone R08-5I1) (CAT#: VS3-FY1790)

• Immunogen
• Recombinant human NDUFB10 protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human NDUFB10

• Species Reactivity
• Human

• Clone
• R08-5I1

• Applications
• Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 21 kDa, while the observed molecular weight stands at 21 kDa.

• Related Disease
• Mitochondrial Complex I Deficiency, Nuclear Type 35 and Isolated Complex I Deficiency

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunohistochemistry: 1/50-1/100
  Immunofluorescence: 1/50-1/200
  Immunoprecipitation: 1/20

• Alternative Names
• NADH:Ubiquinone Oxidoreductase Subunit B10; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10, 22kDa; NADH-Ubiquinone Oxidoreductase PDSW Subunit; Complex I PDSW Subunit; Complex I-PDSW; CI-PDSW

• Gene ID
• 4716

• UniProt ID
• O96000

• Sequence Similarities
• Belongs to the complex I NDUFB10 subunit family.

• Cellular Localization
• Membrane, Mitochondrion, Mitochondrion inner membrane

• Post Translation Modifications
• The formation of intramolecular disulfide bonds is assisted by CHCHD4 and ensures folding, import into the mitochondrion and is required for the function in mitochondrial respiratory chain complex I assembly. (O96000-NDUBA_HUMAN)
  Ubiquitination at Lys91, Lys121, and Lys131 (NX_O96000 [NX_O96000-1])
  Modification sites at PhosphoSitePlus (O96000)
  Glycosylation from GlyGen (O96000) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_004539.1

• Function
• Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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