Rabbit Anti-NECTIN2 Recombinant Antibody (VS13-YC780) (CAT#: VS13-YC780)

• Immunogen
• Recombinant human Nectin 2.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human NECTIN2

• Species Reactivity
• Human

• Applications
• IHC-P

• Conjugate
• NONE

• Related Disease
• Herpes Simplex and Cleft Lip/Palate-Ectodermal Dysplasia Syndrome

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.

• Preservative
• 0.02% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Immunohistochemistry (IHC): 1/100-1/200

• Alternative Names
• Nectin Cell Adhesion Molecule 2; Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B); PVRL2; HVEB; PRR2; Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B;

• Gene ID
• 5819

• UniProt ID
• Q92692

• Long Name
• Nectin Cell Adhesion Molecule 2

• Sequence Similarities
• Belongs to the nectin family.

• Cellular Localization
• Cell membrane

• Protein Refseq
• XP_047295125.1; XP_054177604.1; NP_001036189.1; NP_002847.1

• Function
• Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.
  Probable cell adhesion protein.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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