Anti-NES (clone W24V115) Recombinant Antibody Coupled Liposome (VS-1024-FY117) (CAT#: VS-1024-FY117)

• Potential Clinical Applications
• Glioma

• Clone
• W24V115

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant mouse monoclonal antibody designed to specifically target human nestin (NES). Nestin is an intermediate filament protein that plays a crucial role in the development of the nervous system and is often used as a marker for neural stem cells. By binding selectively to human NES, this antibody can be an invaluable tool for research and therapeutic applications related to neurodevelopmental studies and regenerative medicine.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• NES

• Introduction
• This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.

• Alternative Names
• Nestin

• Full Name
• Nestin

• Gene ID
• 10763

• UniProt ID
• P48681

• Sequence Similarities
• Belongs to the intermediate filament family.

• Post Translation Modifications
• Constitutively phosphorylated.
  This increases during mitosis when the cytoplasmic intermediate filament network is reorganized (By similarity).
  ( P48681-NEST_HUMAN )
  Modification sites at PhosphoSitePlus ( P48681 )
  Modification sites at neXtProt ( NX_P48681 )
  Glycosylation from GlyGen (P48681) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_006608.1

• Function
• Required for brain and eye development.
  Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division.

• VS-1024-FY67
• Anti-NES (clone W24V66) Recombinant Antibody Coupled Liposome (VS-1024-FY67)

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