Mouse Anti-NFL (pSer473) Recombinant Antibody (VS-0224-FY24) (CAT#: VS-0224-FY24)

The antibody is designed to specifically target pSer473 in the NFL. This mouse monoclonal antibody demonstrates high specificity and has been rigorously tested for its efficacy in Immunohistochemistry and Western Blotting, particularly in its ability to target the Neurofilament light polypeptide phosphorylated on Ser473.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • Linear peptide conjugated with KLH corresponding to the 15 amino acids surrounding phosphorylated serine 473.
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • It detects Neurofilament light polypeptide phosphorylated on Serine 473 in human and mouse cells.
  • Species Reactivity
  • Human, Mouse
  • Applications
  • Western Blot, Immunohistochemistry
  • Conjugate
  • Unconjugated
  • Related Disease
  • Charcot-Marie-Tooth Disease, Demyelinating, Type 1F and Charcot-Marie-Tooth Disease, Dominant Intermediate G

Product Property

  • Purity
  • >95%
  • Format
  • Liquid
  • Buffer
  • 0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl.
  • Preservative
  • 0.05% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western blot: 1/500

Target

  • Alternative Names
  • Neurofilament Light; Protein Phosphatase 1, Regulatory Subunit 110; Neurofilament, Light Polypeptide 68kDa; Neurofilament Triplet L Protein; NF-L; NF68; NFL; Light Molecular Weight Neurofilament Protein; Neurofilament Protein, Light Chain; NFL pSer473

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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