Mouse Anti-NHP GRIN2B Recombinant Antibody (clone B3-13B11) (CAT#: VS-1024-XY344)
Targeting GRIN2B, this antibody exhibits exceptional reactivity with dog, human, non-human primate, and rat specimens. The immunogen, an NMDA receptor 2B fusion protein, ensures a strong and specific response. Its versatility spans various applications, including Western Blotting (WB), Immunohistochemistry (IHC), and ELISA, making it an essential reagent for elucidating neurophysiological mechanisms. With its proven reliability and specificity, this mouse-derived antibody is poised to enhance research focused on synaptic transmission and neurological disorders, providing critical insights into the function of glutamatergic signaling.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_9_5.jpg
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_9_5.jpg
Figure 3 Cerebellum
(Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_7_8.jpg
(Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_7_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (CACO-2, NTERA-2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000273079-GRIN2B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000273079-GRIN2B
Specifications
- Immunogen
- NMDA receptor 2B fusion protein
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- GRIN2B
- Species Reactivity
- Dog, Human, Non-human primate, Rat
- Clone
- B3-13B11
- Applications
- WB, IHC, ELISA
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1-5 µg/mL, IHC: 5-10 µg/mL, ELISA: 3-5 µg/mL
Target
- Alternative Names
- Glutamate Ionotropic Receptor NMDA Type Subunit 2B; Glutamate Receptor; Ionotropic; N-Methyl D-Aspartate 2B; Glutamate [NMDA] Receptor Subunit Epsilon-2; N-Methyl D-Aspartate Receptor Subtype 2B; N-Methyl-D-Aspartate Receptor Subunit 3; NMDAR2B; GluN2B; NR2B;
- Gene ID
- 2904
- UniProt ID
- Q13224
Recommended Products
Recommended Dilution Buffer
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2170MZ | Recombinant Mouse Anti-Human GRIN2B Antibody (clone 24B22) | ICC, IHC-G, WB | Mouse antibody |
| FAMAB-1390CQ | Mouse Anti-Grin2b Recombinant Antibody (clone 17) | ELISA | Mouse IgG1 |
| VS-0522-LC194 | Mouse Anti-GRIN2B Recombinant Antibody (VS-0522-LC194) | ICC, IP, KO/KD-WB, WB, IF, IHC | Mouse IgG2a |
| VS-0522-LC195 | Rat Anti-GRIN2B Recombinant Antibody (VS-0522-LC195) | ICC, IP, KO/KD-WB, WB, IF, IHC | Rat IgG2b |
| VS-0522-LC196 | Human Anti-GRIN2B Recombinant Antibody (VS-0522-LC196) | ICC, IP, KO/KD-WB, WB, IF, IHC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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