Mouse Anti-NHP GRIN2B Recombinant Antibody (clone B3-13B11)
CAT#: VS-1024-XY344
Targeting GRIN2B, this antibody exhibits exceptional reactivity with dog, human, non-human primate, and rat specimens. The immunogen, an NMDA receptor 2B fusion protein, ensures a strong and specific response. Its versatility spans various applications, including Western Blotting (WB), Immunohistochemistry (IHC), and ELISA, making it an essential reagent for elucidating neurophysiological mechanisms. With its proven reliability and specificity, this mouse-derived antibody is poised to enhance research focused on synaptic transmission and neurological disorders, providing critical insights into the function of glutamatergic signaling.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_9_5.jpg
Normal Tissue
Figure 3 Cerebellum
Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69762/154297_B_7_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (CACO-2, NTERA-2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000273079-GRIN2B
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Specifications
- Immunogen
- NMDA receptor 2B fusion protein
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- GRIN2B
- Species Reactivity
- Dog, Human, Non-human primate, Rat
- Clone
- B3-13B11
- Applications
- WB, IHC, ELISA
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1-5 µg/mL, IHC: 5-10 µg/mL, ELISA: 3-5 µg/mL
Target
- Alternative Names
- Glutamate Ionotropic Receptor NMDA Type Subunit 2B; Glutamate Receptor; Ionotropic; N-Methyl D-Aspartate 2B; Glutamate [NMDA] Receptor Subunit Epsilon-2; N-Methyl D-Aspartate Receptor Subtype 2B; N-Methyl-D-Aspartate Receptor Subunit 3; NMDAR2B; GluN2B; NR2B;
- Gene ID
- 2904
- UniProt ID
- Q13224
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "GRIN2B"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1835z | Mouse Anti-GRIN2B Recombinant Antibody (clone 37D8) | WB, ICC, IHC, IP | Mouse IgG2b |
| MOB-2170MZ | Recombinant Mouse Anti-Human GRIN2B Antibody (clone 24B22) | ICC, IHC-G, WB | Mouse antibody |
| FAMAB-1390CQ | Mouse Anti-Grin2b Recombinant Antibody (clone 17) | ELISA | Mouse IgG1 |
| VS-0824-CJ15 | Mouse Anti-GRIN2B Recombinant Antibody (clone 2) | Inhib | Mouse IgG |
| VS7-HM1033 | Mouse Anti-GRIN2B Recombinant Antibody (clone 6E9A8) | ICC, FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1512 | Rabbit Anti-GRIN2B Recombinant Antibody (clone DS1512AB) | FC, WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY98 | Human Anti-GRIN2B (clone 2) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC700 | Recombinant Anti-Grin2b Vesicular Antibody, EV Displayed (VS-0425-YC700) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2923 | Anti-GRIN2B Immunohistochemistry Kit | IHC | |
| VS-0525-XY2924 | Anti-Mouse GRIN2B Immunohistochemistry Kit | IHC |
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