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    Mouse Anti-NHP SMN1 Recombinant Antibody (clone 2F1) (CAT#: VS-1024-XY486)

    Designed for the detection of SMN1, this mouse monoclonal antibody demonstrates reactivity with human and non-human primate tissues. The immunogen is a purified recombinant fragment of human SMN1, ensuring exceptional specificity. Versatile in application, it is suitable for Western blot (WB), immunohistochemistry (IHC), flow cytometry (FC), and ELISA. This antibody serves as a crucial tool for investigating SMN1 expression and its role in spinal muscular atrophy, facilitating comprehensive research across various experimental settings.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16324/if_selected.jpg
    Figure 3 IF staining of human cell line HEK 293
    Figure 3 IF staining of human cell line HEK 293
    (Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear bodies & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/73601/1729_C10_3_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human gallbladder
    Figure 2 IHC staining of human gallbladder
    (Immunohistochemical staining of human gallbladder shows nuclear and cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69888/151521_A_4_4_selected.jpg
    Figure 4 Testis
    Figure 4 Testis
    (Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/45271/107128_A_6_6.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/45271/107128_A_8_3.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/45271/107128_A_8_8.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/45271/107128_A_9_5.jpg
    Figure 8 Cerebral cortex
    Figure 8 Cerebral cortex
    (Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/45271/107128_B_8_5.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (MOLT-4, NB-4, T-47d, WM-115)
    Figure 9 RNA cell line category: Cell line enhanced (MOLT-4, NB-4, T-47d, WM-115)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172062-SMN1

    Specifications

    • Immunogen
    • Purified recombinant fragment of human SMN1
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • SMN1
    • Species Reactivity
    • Human, Non-human primate
    • Clone
    • 2F1
    • Applications
    • WB, IHC, FC, ELISA

    Product Property

    • Purification
    • Protein A purified
    • Purity
    • >95%, determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • PBS, pH 7.4
    • Storage
    • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    Applications

    • Application Notes
    • WB: 1:500-1:1000, IHC: 1:200-1:800, FC: 1:200-1:400, ELISA: 1:8000

    Target

    • Alternative Names
    • SMA; SMN; SMA1; SMA2; SMA3; SMA4; SMA@; SMNT; BCD541; GEMIN1; TDRD16A; T-BCD541

    Recommended Products

    Recommended Dilution Buffer

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    Please select product type
    Rabbit Monoclonal Antibody Products IgG Antibody Products
    CAT Product Name Application Type
    MOR-3342 Hi-Affi™ Recombinant Rabbit Anti-SMN1 Monoclonal Antibody (DS3342AB) WB, IP, IHC-P IgG

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