Mouse Anti-NHP TREM1 Recombinant Antibody (clone 6B12D1)
CAT#: VS-1024-XY513
Targeting the crucial immune modulator TREM1, this monoclonal antibody demonstrates robust reactivity with human, non-human primate, and rat samples. Its immunogen, a purified recombinant fragment of human TREM1, ensures high specificity and sensitivity in various applications, including Western blotting, flow cytometry, and ELISA. This antibody is an invaluable tool for investigating TREM1's role in inflammatory responses and immune signaling pathways, providing researchers with reliable data for advancing our understanding of immune regulation and related pathologies.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53612/1743_C3_18_cr57fe217b31caf_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5563/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line SuSa
Immunofluorescent staining of human cell line SuSa shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53612/1968_F4_2_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5563/15822_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5563/15822_A_7_3.jpg
Normal Tissue
Figure 6 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5563/15822_A_9_4.jpg
Normal Tissue
Figure 7 Urinary bladder
Urothelial cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5563/15822_A_6_5.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (SuSa, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000124731-TREM1
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Specifications
- Immunogen
- Purified recombinant fragment of human TREM1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- TREM1
- Species Reactivity
- Human, Non-human primate, Rat
- Clone
- 6B12D1
- Applications
- WB, FC, ELISA
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1:500-1:1000, FC: 1:200-1:400, ELISA: 1:8000
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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Secondary Antibody
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2466-sdAb | Recombinant Anti-Human TREM1 VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-167CQ | Human Anti-TREM1 Recombinant Antibody (TAB-167CQ) | ELISA, FC, WB, Block | Humanized antibody |
| TAB-167CQ-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (TAB-167CQ-S(P)) | ELISA, FC, WB, Block | Human scFv |
| TAB-167CQ-F(E) | Human Anti-TREM1 Recombinant Antibody; Fab Fragment (TAB-167CQ-F(E)) | ELISA, FC, WB, Block | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0682-YC | Human Anti-TREM1 Recombinant Antibody (HPAB-M0682-YC) | ELISA, FuncS | Human IgG1 |
| HPAB-M0683-YC | Human Anti-TREM1 Recombinant Antibody (HPAB-M0683-YC) | ELISA, FuncS | Human IgG1 |
| VS3-WK1940 | Recombinant Rabbit Anti-TREM1 Capture Antibody (clone R78-3W-5) | ELISA | Rabbit IgG |
| VS3-WK1941 | Recombinant Rabbit Anti-TREM1 Detection Antibody (clone R57-8H-3) | ELISA | Rabbit IgG |
| VS11-QX141 | Mouse Anti-TREM1 Recombinant Antibody (clone 14F69) | ELISA, FC, Block | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0682-YC-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (HPAB-M0682-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0683-YC-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (HPAB-M0683-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0684-YC-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (HPAB-M0684-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0685-YC-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (HPAB-M0685-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0686-YC-S(P) | Human Anti-TREM1 Recombinant Antibody; scFv Fragment (HPAB-M0686-YC-S(P)) | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0682-YC-F(E) | Human Anti-TREM1 Recombinant Antibody; Fab Fragment (HPAB-M0682-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0689-YC-F(E) | Human Anti-TREM1 Recombinant Antibody; Fab Fragment (HPAB-M0689-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0690-YC-F(E) | Human Anti-TREM1 Recombinant Antibody; Fab Fragment (HPAB-M0690-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0691-YC-F(E) | Human Anti-TREM1 Recombinant Antibody; Fab Fragment (HPAB-M0691-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-0579-FY-F(E) | Human Anti-TREM1 Recombinant Antibody (clone mAb 0333); Fab Fragment | Inhib | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY56 | Mouse Anti-TREM1 Agonistic Antibody (VS-0724-XY56) | FC, Agonistic assays Activity, CyTOF® | Mouse IgG1 |
| VS-0724-XY57 | Rat Anti-Trem1 Agonistic Antibody (VS-0724-XY57) | WB, FC, Agonistic assays, CyTOF®, ICC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY228 | CytoStream™ Rat Anti-TREM1 Recombinant Antibody (VS-0225-XY228) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC229 | Recombinant Anti-TREM1 Vesicular Antibody, EV Displayed (VS-0425-YC229) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7505 | Anti-Mouse TREM1 Immunohistochemistry Kit | IHC |
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