Rabbit Anti-NKX2-2 Recombinant Antibody (VS13-YC812) (CAT#: VS13-YC812)
The Rabbit Anti-NKX2-2 Recombinant Antibody is specific for human NKX2-2. NKX2-2 encodes a homeobox domain protein involved in CNS morphogenesis, acting as a nuclear transcription factor and displaying genomic duplication with NKX2-4. The anti-NKX2-2 antibody can be used for Immunohistochemistry (1/100-1/200).
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Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/11006_B_7_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/11006_B_7_5.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_9_3.jpg
Figure 3 Pancreas
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_1_3.jpg
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_1_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_8_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_8_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3468/10935_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (HAP1, T-47d, U-138 MG, U-2 OS, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125820-NKX2-2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125820-NKX2-2
Specifications
- Immunogen
- Recombinant human Nkx2.2.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NKX2-2
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Oligodendroglioma; Extraosseous Ewing Sarcoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- NK2 Homeobox 2; Homeobox Protein NK-2 Homolog B; NKX2.2; NKX2B; NK2 Transcription Factor Related, Locus 2 (Drosophila); NK2 Transcription Factor Related, Locus 2; NK2 Transcription Factor-Like Protein B; NK-2 (Drosophila) Homolog B; Homeobox Protein Nkx-2.2;
- Gene ID
- 4821
- UniProt ID
- O95096
- Long Name
- NK2 Homeobox 2
- Cellular Localization
- Nucleus
- Protein Refseq
- XP_054179432.1
- Function
- Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity).
May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.
Binds to elements within the NEUROD1 promoter.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "NKX2-2"
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1725MZ | Recombinant Mouse Anti-Human NKX2-2 Antibody (clone QS-2D22) | WB | Mouse antibody |
| VS3-QX819 | Mouse Anti-NKX2-2 Recombinant Antibody (clone 1C3-C8-F8) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-WK157 | Mouse Anti-NKX2-2 Recombinant Antibody (clone H12-E4) | WB, ELISA | Mouse IgG1 |
| VS3-XY3447 | Rabbit Anti-NKX2-2 Recombinant Antibody (clone R05-5E5) | IHC-P, ICC, IF | Rabbit IgG |
| VS7-0425-WR482 | Mouse Anti-NKX2-2 Recombinant Antibody (clone 3E4) | FC | Mouse IgG1 |
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