Rabbit Anti-NOP10 Recombinant Antibody (VS13-YC825) (CAT#: VS13-YC825)
The Rabbit Anti-NOP10 Recombinant Antibody is specific for human NOP10. NOP10, part of H/ACA snoRNPs, participates in rRNA processing and modification, essential for telomerase complex function, with links to diverse functions via related proteins. The anti-NOP10 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- Recombinant human NOP10.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NOP10
- Species Reactivity
- Human
- Applications
- WB, IHC-P
- Conjugate
- NONE
- Related Disease
- Dyskeratosis Congenita, Autosomal Recessive and Pulmonary Fibrosis And Bone Marrow Failure Syndrome, Telomere-Related
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Target
- Alternative Names
- NOP10 Ribonucleoprotein; Nucleolar Protein Family A, Member 3 (H/ACA Small Nucleolar RNPs); Nucleolar Protein Family A Member 3; Homolog Of Yeast Nop10p; Nucleolar Protein 10; SnoRNP Protein NOP10; NOLA3;
- Gene ID
- 55505
- UniProt ID
- Q9NPE3
- Long Name
- NOP10 Ribonucleoprotein
- Sequence Similarities
- Belongs to the NOP10 family.
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_061118.1
- Function
- Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.
This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Recommended Products
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY2052 | Rabbit Anti-NOP10 Recombinant Antibody (clone R05-5C3) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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