Recombinant Armenian hamster Anti-NOTCH1 Antibody (HMN1-12) (CAT#: FN-101CQ)
This product is a Armenian hamster antibody that recognizes NOTCH1. The antibody can be used for immunoassay techniques such as: FC, IHC.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/67168/1315_F7_4_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/67168/1315_F7_4_selected.jpg
Figure 2 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22466/61564_A_3_3_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22466/61564_A_3_3_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_B_8_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_B_8_5.jpg
Figure 4 Colon
(Endocrine cells Staining: Medium Intensity: Moderate Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes - Microvilli Staining: Medium Intensity: Moderate Fibroblasts Staining: High Intensity: Strong Mucosal lymphoid cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_8_3.jpg
(Endocrine cells Staining: Medium Intensity: Moderate Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes Staining: Medium Intensity: Moderate Quantity:>75% Enterocytes - Microvilli Staining: Medium Intensity: Moderate Fibroblasts Staining: High Intensity: Strong Mucosal lymphoid cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_8_5.jpg
Figure 7 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_6_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_6_6.jpg
Figure 8 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8112/61559_A_9_8.jpg
Figure 9 RNA cell line category: Cell line enhanced (HaCaT, HDLM-2, HMC-1, MOLT-4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148400-NOTCH1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148400-NOTCH1
Specifications
- Immunogen
- Purified Recombinant Mouse Notch-1 (>98%)
- Host Species
- Armenian hamster
- Type
- Armenian Hamster IgG
- Specificity
- Mouse
- Species Reactivity
- Mouse
- Clone
- HMN1-12
- Applications
- FC, IHC
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Notch 1; Translocation-Associated Notch Protein TAN-1; TAN1; HN1; Notch (Drosophila) Homolog 1 (Translocation-Associated); Notch Homolog 1, Translocation-Associated (Drosophila); Notch Homolog 1, Translocation-Associated;
- Gene ID
- 18128
- UniProt ID
- Q01705
Related Resources
Breast Cancer
Endocrine Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NOTCH1"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H11 | Anti-Human NOTCH1 Recombinant Antibody (Brontictuzumab) | Inhib | IgG2 - lambda |
| TAB-541MZ | Human Anti-NOTCH1 Recombinant Antibody (TAB-541MZ) | Neut, WB | Humanized antibody |
| TAB-541MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-541MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
| TAB-542MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-542MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
| TAB-544MZ-S(P) | Anti-Human NOTCH1 Recombinant Antibody scFv Fragment (A12.2) | ELISA, WB, Luciferase reporter assay | Humanized antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-660 | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment | ELISA | Human scFv |
| NS-060CN-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6); scFv Fragment | FC, IF, ELISA | Mouse scFv |
| NS-061CN-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10); scFv Fragment | FC, IF, ELISA | Mouse scFv |
| NS-062CN-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11); scFv Fragment | FC, IF, ELISA | Mouse scFv |
| HPAB-0681-WJ-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone h52M51); scFv Fragment | ELISA, WB | Humanized scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-539MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-539MZ-S(P)) | WB, Competition ELISA | Rat scFv |
| TAB-540MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-540MZ-S(P)) | WB, Competition ELISA | Rat scFv |
| TAB-543MZ-S(P) | Anti-Human NOTCH1 Recombinant Antibody scFv Fragment (mAb N248A) | ELISA, WB, Luciferase reporter assay | |
| TAB-539MZ-F(E) | Rat Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-539MZ-F(E)) | WB, Competition ELISA | Rat Fab |
| TAB-540MZ-F(E) | Rat Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-540MZ-F(E)) | WB, Competition ELISA | Rat Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-545MZ-F(E) | Anti-Human NOTCH1 Recombinant Antibody Fab Fragment (23814) | ELISA | Human antibody |
| TAB-546MZ-F(E) | Anti-Human NOTCH1 Recombinant Antibody Fab Fragment (23418.8) | ELISA | Human antibody |
| TAB-547MZ-F(E) | Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-547MZ-F(E)) | ELISA | Human Fab |
| TAB-548MZ-F(E) | Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-548MZ-F(E)) | ELISA | Human Fab |
| TAB-549MZ-F(E) | Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-549MZ-F(E)) | ELISA | Human Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1786CQ | Recombinant Mouse Anti-NOTCH1 Antibody (MHN1-519) | FC, BL | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2473 | Hi-Affi™ Recombinant Rabbit Anti-NOTCH1 Monoclonal Antibody (DS2473AB) | WB, IHC | IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-060CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6) | FC, IF, ELISA, Inhib, FuncS | Mouse IgG1 |
| NS-061CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10) | FC, IF, ELISA | Mouse IgG1 |
| NS-062CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11) | FC, IF, ELISA, Inhib | Mouse IgG2b |
| NS-063CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11) | FC, IF, ELISA | Mouse IgG1 |
| NS-063CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11); Fab Fragment | FC, IF, ELISA | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H11 | Afuco™ Anti-NOTCH1 ADCC Recombinant Antibody (Brontictuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0085-YJ | Rat Anti-NOTCH1 Recombinant Antibody (clone bTAN 20) | IF, IHC, WB | Rat IgG1, κ |
| HPAB-AP750-YC | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133) | ELISA, Block | Human IgG1 |
| HPAB-AP751-YC | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc155) | Block | Human IgG1 |
| HPAB-AP752-YC | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc49) | ELISA | Human IgG1 |
| HPAB-AP753-YC | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc104) | ELISA, FC | Human IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP750-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-AP751-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc155); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-AP752-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc49); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-AP753-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc104); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-AP754-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc629); Fab Fragment | ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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