Mouse Anti-NOXO1 Recombinant Antibody (clone 2506W24)
CAT#: VS-0625-FY54
The Mouse IgG1 kappa monoclonal antibody, clone 2506W24, is designed for detecting NOXO1 in Human, Mouse, and Rat. The immunogen was raised against amino acids 50-339 of mouse NOXO1. With an observed antigen size of about 37 kDa (calculated 51.58 kDa), this antibody is suitable for Western Blot, Immunoprecipitation, Immunofluorescence, and ELISA, providing versatile detection capabilities for NOXO1.
Specifications
- Immunogen
- Antibody raised against mouse NOXO1, targeting amino acids 50-339 at the C-terminus.
- Host Species
- Mouse
- Type
- Mouse IgG1, kappa
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 2506W24
- Applications
- Western Blot, Immunoprecipitation, Immunofluorescence, ELISA
- Related Disease
- Lung Mucoepidermoid Carcinoma and Phagocyte Bactericidal Dysfunction
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >90% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Optimal dilutions for assays should be determined by the user.
Target
- Alternative Names
- NADPH Oxidase Organizer 1; SH3 And PX Domain-Containing Protein 5; NADPH Oxidase Regulatory Protein; Nox-Organizing Protein 1; Nox Organizer 1; SH3PXD5; P41NOX
- Gene ID
- 124056
- UniProt ID
- Q8NFA2
- Long Name
- NADPH Oxidase Organizer 1
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- NP_001254650.1; NP_653204.1; NP_751907.1; NP_751908.1
- Function
- Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
Isoform 3 is more potent than isoform 1 in activating NOX3.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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