AbPlus™ Anti-NTRK1 Magnetic Beads (CBACN-560)
CAT#: VS-0424-XY207
The AbPlus Anti-NTRK1 Magnetic Beads (CBACN-560) is an innovative affinity resin which is bound with anti-NTRK1 specific antibody (CBACN-560). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of NTRK1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76570/1680_E8_5_selected.jpg
Subcellular Location
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35799/ihc_selected.jpg
Subcellular Location
Figure 3 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4606/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Neuronal cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35799/129189_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35799/129189_A_9_3.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:
Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35799/129189_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198400-NTRK1
❮
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-NTRK1 specific antibody (CBACN-560)
- Target
- NTRK1
- Immunogen
- Human NTRK1 (aa 750-850)
- Target Species
- Human, Mouse, Rat
- Antibody Clone
- CBACN-560
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
- Alternative Names
- Neurotrophic Receptor Tyrosine Kinase 1; Neurotrophic Tyrosine Kinase, Receptor, Type 1; High Affinity Nerve Growth Factor Receptor; TRK1-Transforming Tyrosine Kinase Protein; Tropomyosin-Related Kinase A; Tyrosine Kinase Receptor A; EC 2.7.10.1; P140-TrkA; Gp140trk; Trk-A
- Gene ID
- 4914
- UniProt ID
- P04629
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| PABX-182 | Recombinant Mouse Anti-TrkA Antibody (MNAC13) | Neut, FuncS | IgG |
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| CAT | Product Name | Application | Type |
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| MOR-2508 | Hi-Affi™ Recombinant Rabbit Anti-NTRK1 Monoclonal Antibody (DS2508AB) | WB, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0396-CN-S(P) | Human Anti-NTRK1 Recombinant Antibody scFv Fragment (HPAB-0396-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-1359-FY-F(E) | Human Anti-NTRK1 Recombinant Antibody; Fab Fragment (HPAB-1359-FY-F(E)) | ELISA | Humanized Fab |
| HPAB-1360-FY-F(E) | Human Anti-NTRK1 Recombinant Antibody; Fab Fragment (HPAB-1360-FY-F(E)) | ELISA | Humanized Fab |
| HPAB-0659-YJ-S(P) | Mouse Anti-NTRK1 Recombinant Antibody (clone 5C3); scFv Fragment | Agonist, IHC, IF, Inhib | Mouse scFv |
| HPAB-0660-YJ-S(P) | Mouse Anti-NTRK1 Recombinant Antibody (clone ch5C3); scFv Fragment | Agonist, IHC, IF, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0728-CN-F(E) | Mouse Anti-NTRK1 Recombinant Antibody (clone CRB0022); Fab Fragment | WB, ELISA, FC | Mouse Fab |
| HPAB-0729-CN-F(E) | Human Anti-NTRK1 Recombinant Antibody (clone CRB0088); Fab Fragment | WB, ELISA, FC | Human Fab |
| HPAB-0730-CN-F(E) | Human Anti-NTRK1 Recombinant Antibody (clone CRB0089_IgG4); Fab Fragment | WB, ELISA, FC | Human Fab |
| HPAB-0659-YJ-F(E) | Mouse Anti-NTRK1 Recombinant Antibody (clone 5C3); Fab Fragment | Agonist, IHC, IF, Inhib | Mouse Fab |
| HPAB-0660-YJ-F(E) | Human Anti-NTRK1 Recombinant Antibody (clone ch5C3); Fab Fragment | Agonist, IHC, IF, Inhib | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1530-CN | Recombinant Rabbit Anti-NTRK1 Monoclonal Antibody (CBACN-560) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-1531-CN | Recombinant Rabbit Anti-NTRK1 Monoclonal Antibody (CBACN-561) | WB, IF, IHC | Rabbit IgG |
| HPAB-0659-YJ | Mouse Anti-NTRK1 Recombinant Antibody (clone 5C3) | Agonist, IHC, IF, Inhib | Mouse IgG2a, κ |
| HPAB-0660-YJ | Human Anti-NTRK1 Recombinant Antibody (clone ch5C3) | Agonist, IHC, IF, Inhib | Chimeric (mouse/human) IgG1, κ |
| ZG-0091U | Rabbit Anti-NTRK1 Recombinant Antibody (clone 2A5) | ELISA, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC846 | CytoStream™ Rabbit Anti-NTRK1 Recombinant Antibody (VS13-YC846) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC380 | Recombinant Anti-NTRK1 Vesicular Antibody, EV Displayed (VS-0425-YC380) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5016 | Anti-NTRK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5017 | Anti-Mouse NTRK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5018 | Anti-Rat NTRK1 Immunohistochemistry Kit | IHC |
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