Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (HPAB-N0201-YC-F(E))

Name: Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (HPAB-N0201-YC-F(E))
SKU: HPAB-N0201-YC-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-N0201-YC-F(E)

This product is a recombinant human antibody Fab Fragment that recognizes NTRK2. The antibody was purified by affinity chromatography.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7637/202_C1_1_selected.jpg

Normal Tissue Figure 2 High expression in cerebral cortex

Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_B_7_5.jpg

Normal Tissue Figure 3 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_8_5.jpg

Normal Tissue Figure 4 Testis

Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_6_6.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (AF22, HaCaT, RPTEC TERT1, SH-SY5Y, SuSa)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148053-NTRK2

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Specifications

Immunogen
Recombinant human TrkB extracellular domain generated using HEK293-6E cell line expression

Host Species
Human

Derivation
Humanized

Type
Humanized Fab

Specificity
Human NTRK2

Species Reactivity
Human

Applications
FuncS

Related Disease
Neurological Disorders

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Neurotrophic Receptor Tyrosine Kinase 2; Neurotrophic Tyrosine Kinase Receptor Type 2; Tropomyosin-Related Kinase B; EC 2.7.10.1; GP145-TrkB; Trk-B; TRKB; Neurotrophic Tyrosine Kinase, Receptor, Type 2

Gene ID
4915

UniProt ID
Q16620

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Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-N0201-YC-F(E).pdf

MSDS

MSDS - HPAB-N0201-YC-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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HPAB-AP761-YC	Human Anti-NTRK2 Recombinant Antibody (clone 4A6)	FuncS	Humanized IgG
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HPAB-J0198-YC-F(E)	Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (HPAB-J0198-YC-F(E))	ELISA	Human Fab
HPAB-J0199-YC-F(E)	Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (HPAB-J0199-YC-F(E))	ELISA	Human Fab
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HPAB-J0201-YC-F(E)	Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (HPAB-J0201-YC-F(E))	ELISA	Human Fab

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