Mouse Anti-NTRK2 Recombinant Antibody (clone 10B6C4) (CAT#: VS7-0425-WR513)
This product is a mouse IgG1 antibody that binds to human NTRK2. The antibody 10B6C4 recognizes specific amino acid domain of human NTRK2 (AA: 207-339). It can be used for IHC assay.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7637/202_C1_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7637/202_C1_1_selected.jpg
Figure 2 High expression in cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_B_7_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_B_7_5.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (AF22, HaCaT, RPTEC TERT1, SH-SY5Y, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148053-NTRK2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148053-NTRK2
Specifications
- Immunogen
- Recombinant human NTRK2 (AA: 207-339) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human NTRK2
- Species Reactivity
- Human
- Clone
- 10B6C4
- Molecule Class
- Neurotrophic Tyrosine Kinase Receptor (NTKR) Family
- Applications
- IHC
- Conjugate
- Unconjugated
- Related Disease
- Developmental and epileptic encephalopathy 58 (DEE58); Obesity, hyperphagia, and developmental delay (OBHD)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- NTRK2; Tyrosine Kinase Receptor B; Tropomyosin-Related Kinase B; EC 2.7.10; Trk-B; TrkB Tyrosine Kinase; EC 2.7.10.1; GP145-TrkB; Neurotrophic Tyrosine Kinase, Receptor, Type 2; TRKB; BDNF/NT-3 Growth Factors Receptor; Neurotrophic Tyrosine Kinase Recepto
- Gene ID
- 4915
- UniProt ID
- Q16620
- Long Name
- Neurotrophic Receptor Tyrosine Kinase 2
- Cellular Localization
- Cell membrane; Cell projection; Cytoplasm; Endosome; Membrane; Synapse
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001007098.1
- Function
- Developmental protein; Kinase; Receptor; Transferase; Tyrosine-protein kinase
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179CQ | Anti-Human NTRK2 Recombinant Antibody (RN1026A) | ELISA, FC | Humanized antibody |
| TAB-177CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C2) | ELISA, FC | Humanized antibody |
| TAB-178CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (A2) | ELISA, FC | Humanized antibody |
| TAB-179CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (RN1026A) | ELISA, FC | Humanized antibody |
| TAB-177CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (C2) | ELISA, FC | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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