Mouse Anti-NTRK3 Monoclonal Antibody (VS7-0425-WR514) (CAT#: VS7-0425-WR514)
This product is a mouse IgG antibody that binds to human NTRK3. The antibody recognizes specific amino acid domain of human Trk C (aa32-429). It can be used for WB, IHC-P, IF, and ELISA assays.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoli & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27484/if_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoli & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27484/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48065/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48065/if_selected.jpg
Figure 3 Cerebral cortex
(nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_B_7_5.jpg
(nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_B_7_5.jpg
Figure 4 Colon
(nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_8_3.jpg
(nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_8_3.jpg
Figure 5 Testis
(nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_6_6.jpg
(nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_6_6.jpg
Figure 6 Lymph node
(Non-nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_9_8.jpg
(Non-nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enriched (U-138 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140538-NTRK3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140538-NTRK3
Specifications
- Immunogen
- Recombinant human Trk C (aa32-429) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human NTRK3
- Species Reactivity
- Human
- Molecule Class
- Neurotrophic Tyrosine Kinase Receptor (NTKR) Family
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Defects in NTRK3 are associated with susceptibility to congenital heart defects (CHD). A disease characterized by congenital developmental abnormalities involving structures of the heart. CHD are the most common major birth defects and the leading cause of death from congenital malformations
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- NTRK3; Neurotrophic Tyrosine Kinase Receptor Type 3; Tyrosine Kinase Receptor C; TRKC; EC 2.7.10.1; Neurotrophic Tyrosine Kinase, Receptor, Type 3; NT-3 Growth Factor Receptor; Gp145(TrkC); ETV6-NTRK3 Fusion; ETS Related Protein-Neurotrophic Receptor Tyro
- Gene ID
- 4916
- UniProt ID
- Q16288
- Long Name
- Neurotrophic receptor tyrosine kinase 3
- Cellular Localization
- Membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_001007157.1
- Function
- Developmental protein; Kinase; Receptor; Transferase; Tyrosine-protein kinase
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2174z | Mouse Anti-NTRK3 Recombinant Antibody (clone 36A5) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-1790MZ | Recombinant Mouse Anti-Human NTRK3 Antibody (clone 5H6) | ELISA, ICC/IF, WB | Mouse antibody |
| VS3-QX841 | Mouse Anti-NTRK3 Recombinant Antibody (clone 1454CT394.87.35) | WB | Mouse IgG1, κ |
| VS3-XY1193 | Mouse Anti-NTRK3 Recombinant Antibody (clone 4G5) | ELISA, WB | Mouse IgG1 |
| VS3-XY1194 | Mouse Anti-NTRK3 Recombinant Antibody (clone 7H6) | ELISA, WB, IHC | Mouse IgG1 |
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