Mouse Anti-NTRK3 Monoclonal Antibody (VS7-0425-WR514)
CAT#: VS7-0425-WR514
This product is a mouse IgG antibody that binds to human NTRK3. The antibody recognizes specific amino acid domain of human Trk C (aa32-429). It can be used for WB, IHC-P, IF, and ELISA assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to nucleoli & nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27484/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48065/if_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_B_7_5.jpg
Normal Tissue
Figure 4 Colon
nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_8_3.jpg
Normal Tissue
Figure 5 Testis
nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (U-138 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140538-NTRK3
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Specifications
- Immunogen
- Recombinant human Trk C (aa32-429) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human NTRK3
- Species Reactivity
- Human
- Molecule Class
- Neurotrophic Tyrosine Kinase Receptor (NTKR) Family
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Defects in NTRK3 are associated with susceptibility to congenital heart defects (CHD). A disease characterized by congenital developmental abnormalities involving structures of the heart. CHD are the most common major birth defects and the leading cause of death from congenital malformations
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- NTRK3; Neurotrophic Tyrosine Kinase Receptor Type 3; Tyrosine Kinase Receptor C; TRKC; EC 2.7.10.1; Neurotrophic Tyrosine Kinase, Receptor, Type 3; NT-3 Growth Factor Receptor; Gp145(TrkC); ETV6-NTRK3 Fusion; ETS Related Protein-Neurotrophic Receptor Tyro
- Gene ID
- 4916
- UniProt ID
- Q16288
- Long Name
- Neurotrophic receptor tyrosine kinase 3
- Cellular Localization
- Membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_001007157.1
- Function
- Developmental protein; Kinase; Receptor; Transferase; Tyrosine-protein kinase
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NTRK3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2174z | Mouse Anti-NTRK3 Recombinant Antibody (clone 36A5) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-1790MZ | Recombinant Mouse Anti-Human NTRK3 Antibody (clone 5H6) | ELISA, ICC, IF, WB | Mouse antibody |
| VS3-XY1193 | Mouse Anti-NTRK3 Recombinant Antibody (clone 4G5) | ELISA, WB | Mouse IgG1 |
| VS3-XY1194 | Mouse Anti-NTRK3 Recombinant Antibody (clone 7H6) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-WK1038 | Mouse Anti-NTRK3 Recombinant Antibody (VS3-WK1038) | WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-181CQ | Mouse Anti-NTRK3 Recombinant Antibody (TAB-181CQ) | ELISA, IF, WB, FC | Mouse IgG1, κ |
| TAB-183CQ | Anti-Human NTRK3 Recombinant Antibody (2256) | ELISA, WB | |
| TAB-184CQ | Anti-Human NTRK3 Recombinant Antibody (2248) | Agonist, ELISA | |
| TAB-181CQ-S(P) | Mouse Anti-NTRK3 Recombinant Antibody; scFv Fragment (TAB-181CQ-S(P)) | ELISA, FC, IF, WB | Mouse scFv |
| TAB-183CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (2256) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-182CQ | Anti-Human NTRK3 Recombinant Antibody (6.4.1) | ELISA, WB | Human antibody |
| TAB-185CQ | Anti-Human NTRK3 Recombinant Antibody (6.1.2) | ELISA, WB | Human antibody |
| TAB-182CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (6.4.1) | ELISA, WB | Human antibody |
| TAB-185CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (6.1.2) | ELISA, WB | Human antibody |
| TAB-182CQ-F(E) | Anti-Human NTRK3 Recombinant Antibody Fab Fragment (6.4.1) | ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4350 | Hi-Affi™ Recombinant Rabbit Anti-NTRK3 Monoclonal Antibody (SI440DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0198-CN-S(P) | Human Anti-NTRK3 Recombinant Antibody scFv Fragment (HPAB-0198-CN-S(P)) | ELISA, ICC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0198-CN-F(E) | Human Anti-NTRK3 Recombinant Antibody Fab Fragment (HPAB-0198-CN-F(E)) | ELISA, ICC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC221 | Recombinant Anti-NTRK3 Vesicular Antibody, EV Displayed (VS-0425-YC221) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5023 | Anti-NTRK3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5024 | Anti-Mouse NTRK3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC275 | SmartAb™ Recombinant Anti-NTRK3 pH-dependent Antibody (VS-0825-YC275) | ELISA | Human IgG |
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