AbPlus™ Anti-NUMB Magnetic Beads (VS-0724-YC153) (CAT#: VS-0724-YC153)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-NUMB specific antibody

• Target
• NUMB

• Immunogen
• Synthetic peptide corresponding to the C-terminus of the human Numb.

• Target Species
• Human, Mouse

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

• Alternative Names
• NUMB, Endocytic Adaptor Protein; C14orf41; H-Numb; Chromosome 14 Open Reading Frame 41; Numb (Drosophila) Homolog; Numb Homolog (Drosophila);

• Gene ID
• 8650

• UniProt ID
• P49757

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