Rabbit Anti-NUP50 Recombinant Antibody (VS13-YC852) (CAT#: VS13-YC852)
The Rabbit Anti-NUP50 Recombinant Antibody is specific for human NUP50. NUP50 encodes a nucleoporin within the nuclear pore complex, regulating nuclear-cytoplasmic macromolecule transport, and showing splicing-driven isoform diversity. The anti-NUP50 antibody can be used for Western blot (1/500-1/1000), Immunofluorescence (1/50-1/200), Immunoprecipitation (1/20).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/767_F11_1_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/767_F11_1_selected.jpg
Figure 2 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_B_6_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_B_6_4.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_9_8.jpg
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_7_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_7_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47162/109446_A_7_5.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000093000-NUP50
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000093000-NUP50
Specifications
- Immunogen
- Recombinant human NUP50.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NUP50
- Species Reactivity
- Human
- Applications
- WB, ICC, IF, IP
- Conjugate
- NONE
- Related Disease
- Lethal Congenital Contracture Syndrome
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- Nucleoporin 50; 50 KDa Nucleoporin; Nucleoporin 50kDa; Nucleoporin Nup50; NPAP60L; Nuclear Pore-Associated Protein 60 KDa-Like;
- Gene ID
- 10762
- UniProt ID
- Q9UKX7
- Long Name
- Nucleoporin 50
- Cellular Localization
- Membrane; Nuclear pore complex; Nucleus
- Protein Refseq
- XP_006724166.1; XP_011528135.1; XP_024307914.1; XP_047297027.1; XP_047297028.1
- Function
- Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Rabbit Monoclonal Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2525 | Hi-Affi™ Recombinant Rabbit Anti-NUP50 Monoclonal Antibody (DS2525AB) | WB, ICC, FC | IgG |
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For Research Use Only. Not For Clinical Use.
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