Mouse Anti-oligomeric MAPT Recombinant Antibody (clone TOC1) (CAT#: VS-0224-FY9)
This product is a mouse recombinant antibody that recognizes tau. This antibody demonstrates specificity towards amino acids 209-224 of the tau oligomeric complex.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line MCF7 shows localization to nuclear speckles & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48895/1070_E6_2_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nuclear speckles & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48895/1070_E6_2_selected.jpg
Figure 2 IF staining of human cell line BJ
(Immunohistochemical staining of human appendix shows strong positivity in peripheral ganglia and nerve fibers.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69524/156431_A_3_2_selected.jpg
(Immunohistochemical staining of human appendix shows strong positivity in peripheral ganglia and nerve fibers.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69524/156431_A_3_2_selected.jpg
Figure 3 Cerebral cortex
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_B_8_5.jpg
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_B_8_5.jpg
Figure 4 Colon
(Endocrine cells
Staining:
Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_3.jpg
(Endocrine cells
Staining:
Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_3.jpg
Figure 5 Kidney
(Proximal tubules (cell body)
Staining:
Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_5.jpg
(Proximal tubules (cell body)
Staining:
Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_5.jpg
Figure 6 RNA cell line category: Group enriched (HDLM-2, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186868-MAPT
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186868-MAPT
Figure 6 RNA cell line category: Group enriched (HDLM-2, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186868-MAPT
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186868-MAPT
Specifications
- Immunogen
- Immunizing a mouse with electro eluted cross-linked Tau dimers.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- The antibody binds to oligomeric tau.
- Species Reactivity
- Human
- Clone
- TOC1
- Applications
- Western Blot, Immunohistochemistry, ELISA, Immunofluorescence
- Conjugate
- Unconjugated
- Related Disease
- Alzheimer's disease, Pick's disease
Product Property
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.02% Proclin 300
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunofluorescence: 1/1000
Target
- Alternative Names
- Microtubule Associated Protein Tau; G Protein Beta1/Gamma2 Subunit-Interacting Factor 1; Protein Phosphatase 1, Regulatory Subunit 103; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPTL; MTBT1; TAU
- Gene ID
- 4137
- UniProt ID
- P10636
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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