SmartAb™ Recombinant Anti-OPN pH-dependent Antibody (Clone 23C3)

CAT#: VS-0825-YC4

This acid-switched antibody targets human osteopontin (OPN) in a pH-dependent manner. It demonstrates stronger binding to OPN at neutral pH but releases the antigen in the acidic environment of the endosome. Human OPN is a multifunctional secreted protein implicated in a wide range of biological processes, including bone mineralization, inflammation, and cell adhesion. Serving as a signaling molecule, OPN is highly expressed in inflammatory conditions, positioning it as a key player in both normal physiology and disease states.

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human Osteopontin
  • Species Reactivity
  • Human
  • Clone
  • 23C3
  • Applications
  • WB, ELISA

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A purified
  • Purity
  • >95%, determined by SDS-PAGE and SEC-HPLC
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • For short-term storage, keep it at 4°C for up to two weeks. For long-term storage, divide the solution into aliquots and freeze them at -20°C or below.

Target

  • Alternative Names
  • OPN; Osteopontin; bone sialoprotein I; BSP-1; BNSP; early T-lymphocyte activation; ETA-1; secreted phosphoprotein 1; SPP1; Ric
  • Long Name
  • Osteopontin
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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CAT Product Name Application Type
PSBL-291 Mouse Anti-OPN Recombinant Antibody (clone 23C3); scFv Fragment WB, ELISA, FuncS Mouse scFv
CAT Product Name Application Type
PFBL-291 Mouse Anti-OPN Recombinant Antibody (clone 23C3); Fab Fragment WB, ELISA, FuncS Mouse Fab
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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