Mouse Anti-OVA Recombinant Soluble TCR (clone (OT-1)-1)

CAT#: scTCR-0787YC-S(P)

Recombinant Mouse single-chain TCR (scTCR) OT-1 recognizes Ovalbumin (OVA) antigen variant E1 (EIINFEKL) in the context of H2-Kᵇ. The scTCR is responsible for the specificity of T cells.

Specifications

  • Host Species
  • Mouse
  • Target
  • OVA
  • Epitope
  • EIINFEKL
  • MHC
  • H2-Kᵇ
  • Clone
  • OT-1
  • Type
  • Single-Chain TCR

Target

  • Alternative Names
  • Ovalbumin (OVA) antigen variant E1; EIINFEKL
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Breast cancer biomarkers at key points during disease progression
Useful For Antigen Variant Studies
We purchased this recombinant single-chain TCR to investigate T cell specificity in our mouse models. The product arrived in excellent condition, and we were able to successfully use it to recognize the Ovalbumin antigen variant E1 in the context of H2-Kb.
Breast cancer biomarkers at key points during disease progression
Reliable OT-1 Clone Specificity
This soluble TCR based on the OT-1 clone worked exactly as described for our binding assays. It showed clear specificity for the EIINFEKL peptide sequence, which was critical for our comparative studies on TCR-ligand interactions.

Q&As

  1. Which specific antigen variant does this OT-1 clone recognize?

    A: This recombinant mouse single-chain TCR (OT-1) is designed to recognize the Ovalbumin (OVA) antigen variant E1. The specific peptide sequence it targets is EIINFEKL, and it does so in the context of H2-Kb.

  2. Does this protein act as a serine protease inhibitor?

    A: No, although Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, it is not a serine protease inhibitor. This product is a TCR that recognizes the ovalbumin peptide, which accounts for approximately 55% of the total protein in egg white.

View the frequently asked questions answered by Creative Biolabs Support.

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