Mouse Anti-OVA Recombinant Soluble TCR (clone (OT-1)-2)

CAT#: scTCR-0788YC-S(P)

Recombinant Mouse single-chain TCR (scTCR) OT-1 recognizes Ovalbumin (OVA) antigen variant A2 (SAINFEKL) in the context of H2-Kᵇ. The scTCR is responsible for the specificity of T cells.

Specifications

  • Host Species
  • Mouse
  • Target
  • OVA
  • Epitope
  • SAINFEKL
  • MHC
  • H2-Kᵇ
  • Clone
  • OT-1
  • Type
  • Single-Chain TCR

Target

  • Alternative Names
  • Ovalbumin (OVA) antigen variant A2; SAINFEKL
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Breast cancer biomarkers at key points during disease progression
Specific To Variant A2
We required a TCR that could distinguish the OVA antigen variant A2, and the OT-1 clone in this product did exactly that. It recognized the SAINFEKL sequence in the context of H2-Kb perfectly for our comparative analysis.
Breast cancer biomarkers at key points during disease progression
Consistent Recombinant Product
As part of our study on the serpin superfamily, we used this mouse soluble TCR to validate peptide recognition. The product performed consistently across different assays, confirming its specificity for the targeted Ovalbumin peptide.

Q&As

  1. What is the difference between this product and other OT-1 clones?

    A: This specific product utilizes the OT-1 clone to recognize the Ovalbumin (OVA) antigen variant A2. The target peptide sequence for this variant is SAINFEKL, which differs from other variants like E1 or R4.

  2. Is Ovalbumin a protease inhibitor?

    A: No, Ovalbumin is not a serine protease inhibitor, even though it displays sequence and three-dimensional homology to the serpin superfamily. It is the main protein found in egg white and is often used in antigen research.

View the frequently asked questions answered by Creative Biolabs Support.

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