Mouse Anti-OxPL Recombinant Antibody (clone E06) (CAT#: HPAB-0399-YJ)
This product is a recombinant mouse antibody that recognizes human OxPL. It can be used for treating CAS.
Specific Inquiry
FuncS
Figure 1 provides that E06-scFv reduced the oxPL/apoB ratio in the plasma of transgenic mice fed high cholesterol diets.
FuncS
Figure 2 provides the results of mouse serum amyloid A (SAA1) assays.
SAA is an acute phase serum protein marker that is elevated in mice approximately 50-fold following LPS injection. Serum amyloid A (SAA1 and SAA2) are a family of apolipoproteins secreted as a 103aa (12 kDa) polypeptide and circulated as part of the HDL complex. SAA enhances the binding of HDL's to macrophages and helps the delivery of lipid to sites of injury for use in tissue repair.
FuncS
Figure 3 shows that LDLR−/−/E06 transgenic mice live longer compared to LDLR−/− controls.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human OxPL
- Species Reactivity
- Human
- Clone
- E06
- Applications
- ELISA, FuncS
- Related Disease
- Calcific aortic stenosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.
Target
- Alternative Names
- Oxidized phospholipids
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone E06"
See other products for "OxPL"
Select a product category from the dropdown menu below to view related products.
Please select product type
scFv Fragment Antibody
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0399-YJ-S(P) | Mouse Anti-OxPL Recombinant Antibody (clone E06); scFv Fragment | ELISA, FuncS | Mouse scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0399-YJ. Click the button above to contact us or submit your feedback about this product.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# HPAB-0399-YJ, RRID: AB_3111395)
Copy citation
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: Inhib, ELISA, FC, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
