This product is a recombinant Human antibody that can recognize PCSK9. The antibody can recognize epitopes within the HSPG binding domain.
Figure 1 mAbs were tested by IP.
Fifteen mAbs specifically precipitated radioactive-labeled PCSK9.
Gustafsen, C., Olsen, D., Vilstrup, J., Lund, S., Reinhardt, A., Wellner, N., ... & Seeberger, P. H. (2017). Heparan sulfate proteoglycans present PCSK9 to the LDL receptor. Nature communications, 8(1), 503.
Figure 2 Co-injection of PCSK9 (10 µg) with mAb 5E11 (50 µg) protects the LDLR from degradation (control n = 4, PCSK9 n = 7, PCSK9/mAb 5E11 n = 6).
Representative blot is shown.
Gustafsen, C., Olsen, D., Vilstrup, J., Lund, S., Reinhardt, A., Wellner, N., ... & Seeberger, P. H. (2017). Heparan sulfate proteoglycans present PCSK9 to the LDL receptor. Nature communications, 8(1), 503.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H10 | Anti-Human PCSK9 Recombinant Antibody (Bococizumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG2 - kappa |
TAB-H59 | Anti-Human PCSK9 Recombinant Antibody (Ralpancizumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG2 - kappa |
TAB-764CL | Human Anti-PCSK9 Recombinant Antibody (TAB-764CL) | ELISA | Human IgG |
TAB-0020CL | Anti-Human PCSK9 Recombinant Antibody (LPD1282/LPD1462 {i.e., antibody 1 F11)) | LDL-c uptake assay | Humanized Antibody |
TAB-0020CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (LPD1282/LPD1462 {i.e., antibody 1 F11)) | LDL-c uptake assay | Humanized Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0956CL | Anti-Human PCSK9 Recombinant Antibody (m7F8) | ELISA | |
TAB-0960CL | Anti-Human PCSK9 Recombinant Antibody (Ab1) | ELISA | Rabbit mAb |
TAB-0956CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (m7F8) | ELISA | |
TAB-0960CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (Ab1) | ELISA | Rabbit mAb |
TAB-0956CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (m7F8) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0959CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0959CL-S(P)) | ELISA, FC | Human scFv |
TAB-0953CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0953CL-F(E)) | ELISA | Human Fab |
TAB-0954CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0954CL-F(E)) | WB | Human Fab |
TAB-0955CL-F(E) | Mouse Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0955CL-F(E)) | WB | Mouse Fab |
TAB-0959CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0959CL-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABC-196 | Human Anti-PCSK9 Recombinant Antibody (clone J16) | IF, IP, WB, ELISA | Human IgG |
HPAB-N0377-YC | Human Anti-PCSK9 Recombinant Antibody (HPAB-N0377-YC) | FC, FuncS | Human IgG |
MRO-1187-CN | Recombinant Mouse Anti-PCSK9 Monoclonal Antibody (2F1) | WB, IHC, IF, FC | Mouse IgG2b |
MRO-1188-CN | Recombinant Mouse Anti-PCSK9 Monoclonal Antibody (2F2) | IHC, IF, FC | Mouse IgG2b |
HPAB-0309-FY | Human Anti-PCSK9 Recombinant Antibody (clone 8F5) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0080CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKE2) | FuncS, Inhib, FC, WB | Single domain antibody |
TAB-0081CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKF8) | FuncS, Inhib, FC, WB | Single domain antibody |
TAB-0082CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKG1) | FuncS, Inhib, FC, WB | Single domain antibody |
TAB-0083CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (P1.70) | FuncS, Inhib, FC, WB | Single domain antibody |
TAB-0084CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKE1) | FuncS, Inhib, FC, WB | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1826CQ | Recombinant Human Anti-PCSK9 Antibody, Unconjugated | Neut | IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2618 | Hi-Affi™ Recombinant Rabbit Anti-PCSK9 Monoclonal Antibody (DS2618AB) | WB | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0309-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody (clone 8F5); Fab Fragment | ELISA | Human Fab |
HPAB-0310-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody (clone 3D1); Fab Fragment | ELISA | Human Fab |
HPAB-0311-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody (clone 7c4); Fab Fragment | ELISA | Human Fab |
HPAB-0312-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody (clone 5C2); Fab Fragment | ELISA | Human Fab |
HPAB-0313-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody (clone 4E9); Fab Fragment | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-758 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Lodelcizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-H10 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Bococizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
AFC-TAB-H59 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Ralpancizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-H31 | Afuco™ Anti-PCSK9 Recombinant Antibody (AFC-TAB-H31), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0511-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0511-FY-S(P)) | Neut | Human scFv |
HPAB-0512-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0512-FY-S(P)) | Neut | Human scFv |
HPAB-0479-YJ-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0479-YJ-S(P)) | ELISA, Inhib, FuncS | Human scFv |
HPAB-0480-YJ-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0480-YJ-S(P)) | ELISA, Inhib, FuncS | Human scFv |
HPAB-0724YY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0724YY-S(P)) | ELISA | Human scFv |
There are currently no Customer reviews or questions for PABC-505. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.