Human Anti-PCSK9 Recombinant Antibody (clone PA4) (CAT#: HPAB-1439LY)
This product is an antibody that recognizes PCSK9. The antibody PA4 can be used for immunoassay techniques such as: ELISA, Blocking.
Specific Inquiry
WB
Figure 1 Western blot analysis for PCSK9 with or without PA4-IgG4, and LDLR mAb in HepG2 cells.
HepG2 cells were treated for 24 h with 15 mg/ml PCSK9 with or without PA4-IgG4 (20 mg/ml), and LDLR was quantified by western blot analysis.
Cao, Y., Yang, H., Zhou, X., Mao, H., Gao, T., Hu, Z., ... & Guo, Z. (2015). Selection and characterization of human PCSK9 antibody from phage displayed antibody library. Biochemical and biophysical research communications, 463(4), 712-718.
ELISA
Figure 2 ELISA analysis of the binding of the IgG1-PA4 to immobilized PCSK9.
Various amounts of PA4 mab were added to 96-well plates coated with PCSK9 (1 mg/ml), normal human IgG was used as control.
Cao, Y., Yang, H., Zhou, X., Mao, H., Gao, T., Hu, Z., ... & Guo, Z. (2015). Selection and characterization of human PCSK9 antibody from phage displayed antibody library. Biochemical and biophysical research communications, 463(4), 712-718.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG
- Specificity
- Human PCSK9
- Species Reactivity
- Human
- Clone
- PA4
- Applications
- WB, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The PCSK9 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia, Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1;
- Gene ID
- 255738
- UniProt ID
- Q8NBP7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1775z | Mouse Anti-PCSK9 Recombinant Antibody (clone 40B4) | WB, ELISA, IF, IP | Mouse IgG1, κ |
| PABZ-101 | Human Anti-PCSK9 Recombinant Antibody (clone 1D05) | ELISA, WB, Neut | Human IgG2 |
| HPAB-0810-CN | Human Anti-PCSK9 Recombinant Antibody (HPAB-0810-CN) | ELISA | Human IgG |
| HPAB-667-FY | Human Anti-PCSK9 Recombinant Antibody (HPAB-667-FY) | Inhib, SPR, ELISA | Human IgG2 |
| HPAB-668-FY | Human Anti-PCSK9 Recombinant Antibody (HPAB-668-FY) | Inhib, SPR | Human IgG2 |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H31 | Human Anti-PCSK9 Recombinant Antibody (TAB-H31) | FC, IP, ELISA, Neut, FuncS, IF, IHC | Human IgG2, λ |
| TAB-0953CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0953CL-F(E)) | ELISA | Human Fab |
| TAB-0954CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0954CL-F(E)) | WB | Human Fab |
| TAB-0955CL-F(E) | Mouse Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0955CL-F(E)) | WB | Mouse Fab |
| TAB-0959CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0959CL-F(E)) | ELISA, FC | Human Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H10 | Anti-Human PCSK9 Recombinant Antibody (Bococizumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG2 - kappa |
| TAB-H59 | Anti-Human PCSK9 Recombinant Antibody (Ralpancizumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG2 - kappa |
| TAB-764CL | Human Anti-PCSK9 Recombinant Antibody (TAB-764CL) | ELISA | Human IgG |
| TAB-0020CL | Anti-Human PCSK9 Recombinant Antibody (LPD1282/LPD1462 {i.e., antibody 1 F11)) | LDL-c uptake assay | Humanized Antibody |
| TAB-0020CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (LPD1282/LPD1462 {i.e., antibody 1 F11)) | LDL-c uptake assay | Humanized Antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-294 | Human Anti-PCSK9 Recombinant Antibody (clone mAb1); scFv Fragment | WB, Block, FuncS | Human scFv |
| HPAB-0318-YJ-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0318-YJ-S(P)) | Antagonist, ELISA, FuncS | Human scFv |
| HPAB-1596-FY-F(E) | Mouse Anti-PCSK9 Recombinant Antibody; Fab Fragment (HPAB-1596-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-0479-YJ-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0479-YJ-S(P)) | ELISA, Inhib, FuncS | Human scFv |
| HPAB-0480-YJ-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0480-YJ-S(P)) | ELISA, Inhib, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-294 | Human Anti-PCSK9 Recombinant Antibody (clone mAb1); Fab Fragment | WB, Block, FuncS | Human Fab |
| PFBZ-101 | Human Anti-PCSK9 Recombinant Antibody (clone 1D05); Fab Fragment | ELISA, WB, Neut | Human Fab |
| PSBC-196 | Human Anti-PCSK9 Recombinant Antibody (clone J16); scFv Fragment | ELISA | Human scFv |
| HPAB-0234-YC-F(E) | Mouse Anti-PCSK9 Recombinant Antibody; Fab Fragment (HPAB-0234-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| HPAB-0051-FY-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (HPAB-0051-FY-F(E)) | Inhib | Human Fab, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0956CL | Anti-Human PCSK9 Recombinant Antibody (m7F8) | ELISA | |
| TAB-0960CL | Anti-Human PCSK9 Recombinant Antibody (Ab1) | ELISA | Rabbit mAb |
| TAB-0956CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (m7F8) | ELISA | |
| TAB-0956CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (m7F8) | ELISA | |
| TAB-0960CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (Ab1) | ELISA | Rabbit mAb |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0080CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKE2) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0081CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKF8) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0082CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKG1) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0083CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (P1.70) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0084CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (PKE1) | FuncS, Inhib, FC, WB | Single domain antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1826CQ | Recombinant Human Anti-PCSK9 Antibody, Unconjugated | Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2618 | Hi-Affi™ Recombinant Rabbit Anti-PCSK9 Monoclonal Antibody (DS2618AB) | WB | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-758 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Lodelcizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H10 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Bococizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
| AFC-TAB-H59 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody (Ralpancizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-H31 | Afuco™ Anti-PCSK9 Recombinant Antibody (AFC-TAB-H31), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, λ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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