Mouse Anti-PDCD1 Recombinant Antibody Hexamer (VS-0924-YC142), CDC Enhanced

Name: Mouse Anti-PDCD1 Recombinant Antibody Hexamer (VS-0924-YC142), CDC Enhanced
SKU: VS-0924-YC142
Rating: 5 (1 reviews)

CAT#: VS-0924-YC142

The product is a mouse anti-PDCD1 antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets human PDCD1 and contains mutations that enhance hexamerization, promoting optimal C1q binding and thereby improving CDC.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1

❮

❯

Specifications

Host Species
Mouse

Type
Antibody hexamer

Specificity
Human PDCD1

Species Reactivity
Human

Molecule Class
~ 900 kDa

Applications
ELISA, Block, CDC

Conjugate
None

Product Property

Clonality
Monoclonal

Purification
Protein G purified

Purity
>95% determined as SDS-PAGE and SEC-HPLC

Aggregation
<5%

Buffer
PBS, pH 7.4

Preservative
No preservatives

Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1;

Gene ID
5133

UniProt ID
Q15116

Long Name
Programmed Cell Death 1

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Datasheet

Datasheet - VS-0924-YC142.pdf

MSDS

MSDS - VS-0924-YC142.pdf

COA

Certificate of Analysis Lookup

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