Human Anti-PDCD1 Recombinant Antibody (clone 949); scFv Fragment (CAT#: HPAB-1597-FY-F(E))
This product is a recombinant Antibody scFv Fragment that recognizes PDCD1. The monoclonal Antibody scFv Fragment 949 reacts with the epitope of PDCD1. A control anti-PD-1 antibody with known ligand blocking properties did block PD-L2 binding to PD-1 expressing cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
(Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
(Germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1
Specifications
- Immunogen
- Recombinant human PD-1
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized scFv
- Specificity
- Human PDCD1
- Species Reactivity
- Human
- Clone
- 949
- Applications
- Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1
- Gene ID
- 5133
- UniProt ID
- Q15116
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-295 | Human Anti-PDCD1 Recombinant Antibody (clone CBL42Q); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| HPAB-0214-YJ-S(P) | Human Anti-PDCD1 Recombinant Antibody (HPAB-0214-YJ-S(P)); scFv Fragment | Block, SPR, Neut, FC, FuncS | Human scFv |
| HPAB-0215-YJ-S(P) | Human Anti-PDCD1 Recombinant Antibody (HPAB-0215-YJ-S(P)); scFv Fragment | Block, SPR, FC, FuncS | Human scFv |
| HPAB-0216-YJ-S(P) | Human Anti-PDCD1 Recombinant Antibody (HPAB-0216-YJ-S(P)); scFv Fragment | Block, SPR, FC, FuncS | Human scFv |
| HPAB-2469LY-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-2469LY-S(P)) | ELISA | Humanized scfv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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