Anti-PDGFRL (clone W24V148) Recombinant Antibody Coupled Liposome (VS-1024-FY148) (CAT#: VS-1024-FY148)

• Potential Clinical Applications
• Colorectal cancer

• Clone
• W24V148

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant mouse monoclonal antibody that has been meticulously engineered to selectively bind to the Platelet-Derived Growth Factor Receptor-Like (PDGFRL). This innovative antibody is developed using advanced biotechnological techniques, allowing for high specificity and affinity towards PDGFRL, a receptor involved in various biological processes, including cell proliferation, differentiation, and angiogenesis.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• PDGFRL

• Introduction
• This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

• Alternative Names
• PDGFRL; Platelet-Derived Growth Factor Receptor-Like Protein; PDGRL; Platelet-Derived Growth Factor Receptor-Like; Platelet-Derived Growth Factor-Beta-Like Tumor Suppressor; PDGFR-Like Protein

• Full Name
• Platelet Derived Growth Factor Receptor Like

• Gene ID
• 5157

• UniProt ID
• Q15198

• Cellular Localization
• Secreted

• Post Translation Modifications
• Glycosylation at Asn132 and Asn219 ( NX_Q15198 [NX_Q15198-1] )
  Modification sites at PhosphoSitePlus ( Q15198 )
  Glycosylation from GlyConnect PGFRL_HUMAN (1609)
  Glycosylation from GlyGen (Q15198) 2 sites, 3 N-linked glycans (1 site)

• Protein Refseq
• NP_001359002.1; NP_006198.1

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