Specifications

Host Species
Mouse

Type
Mouse IgG1

Specificity
Human PDSS2

Species Reactivity
Human

Clone
ZN177

Applications
Immunohistochemistry-Paraffin

Conjugate
Unconjugated

Related Disease
Coenzyme Q10 Deficiency, Primary, 3 and Nephrotic Syndrome

Product Property

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS (pH 7.3), 1% BSA, 50% glycerol

Preservative
0.02% Sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Decaprenyl Diphosphate Synthase Subunit 2; Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2; All-Trans-Decaprenyl-Diphosphate Synthase Subunit 2; Decaprenyl Pyrophosphate Synthase Subunit 2; C6orf210; DLP1; Decaprenyl Pyrophosphate Synthetase Subunit 2; Subunit 2 Of Decaprenyl Diphosphate Synthase

Gene ID
57107

UniProt ID
Q86YH6

Sequence Similarities
Belongs to the FPP/GGPP synthase family.

Cellular Localization
Mitochondrion

Protein Refseq
NP_065114.3

Function
Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone.
Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively.
The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
May play a role during cerebellar development (By similarity).
May regulate mitochondrial respiratory chain function (By similarity).

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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