Specifications

Immunogen
Synthetic peptide of human PDZK1

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human PDZK1

Species Reactivity
Human

Clone
R07-2A6

Applications
Western Blot, Immunoprecipitation

MW
The calculated weight of the target protein is approximately 57 kDa, while the observed molecular weight stands at 70 kDa.

Related Disease
Gout and Inflammatory Diarrhea

Product Property

Purification
Affinity Purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
PDZ Domain Containing 1; Na/Pi Cotransporter C-Terminal-Associated Protein 1; Sodium-Hydrogen Exchanger Regulatory Factor 3; CFTR-Associated Protein Of 70 KDa; NaPi-Cap1; NHERF-3; NHERF3; CAP70

Gene ID
5174

UniProt ID
Q5T2W1

Sequence Similarities
Belongs to the NHER family.

Cellular Localization
Cell membrane, Membrane

Post Translation Modifications
Modification sites at PhosphoSitePlus (Q5T2W1)
Modification sites at neXtProt (NX_Q5T2W1)

Protein Refseq
XP_024303387.1; XP_024303388.1; XP_047278483.1; XP_047278484.1; XP_047278485.1

Function
May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney.

Recommended Products

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "PDZK1"

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IgG Antibody Products Rabbit Monoclonal Antibody Products

CAT	Product Name	Application	Type
MOB-3581z	Mouse Anti-PDZK1 Recombinant Antibody (clone 35B5)	WB, IP, IF, ELISA	Mouse IgG1, κ
MOB-1333CT	Recombinant Mouse anti-Human PDZK1 Monoclonal antibody (1A2)	ELISA, WB

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