Rabbit Anti-PF4 Recombinant Antibody (clone R09-7H9)

CAT#: VS3-XY3462

This rabbit recombinant antibody specifically recognizes PF4 (Platelet factor 4), which is a inhibitor of endothelial cell chemotaxis. The antibody specifically reacts with human and rat PF4. It has been tested using Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.

Gene Expression
Figure 1 Bone marrow Figure 2 RNA cell line category: Cell line enriched (HEL)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Rat PF4
  • Species Reactivity
  • Human, Rat
  • Clone
  • R09-7H9
  • Applications
  • WB, IHC-P, IP
  • Related Disease
  • Erythromelalgia; Thrombocytopenia

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100
    IP: 1/20

Target

  • Alternative Names
  • PF-4; CXCL4; SCYB4
  • Long Name
  • Platelet factor 4
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • Modification sites at PhosphoSitePlus (P02776)
    Modification sites at neXtProt (NX_P02776)
  • Function
  • Released during platelet aggregation.
    Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.
    Chemotactic for neutrophils and monocytes.
    Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

Recommended Dilution Buffer

Secondary Antibody

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