Rabbit Anti-PF4 Recombinant Antibody (clone R09-7H9) (CAT#: VS3-XY3462)
This rabbit recombinant antibody specifically recognizes PF4 (Platelet factor 4), which is a inhibitor of endothelial cell chemotaxis. The antibody specifically reacts with human and rat PF4. It has been tested using Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.
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Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52485/126143_B_6_4.jpg
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52485/126143_B_6_4.jpg
Figure 2 RNA cell line category: Cell line enriched (HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163737-PF4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163737-PF4
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat PF4
- Species Reactivity
- Human, Rat
- Clone
- R09-7H9
- Applications
- WB, IHC-P, IP
- Related Disease
- Erythromelalgia; Thrombocytopenia
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- PF-4; CXCL4; SCYB4
- Gene ID
- 5196
- UniProt ID
- P10720
- Long Name
- Platelet factor 4
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P02776)
Modification sites at neXtProt (NX_P02776)
- Protein Refseq
- NP_002610.1
- Function
- Released during platelet aggregation.
Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.
Chemotactic for neutrophils and monocytes.
Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1874-VHH | Recombinant Anti-Human PF4 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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