Human Anti-PfCSP Recombinant Antibody (clone MGU5) (CAT#: FAMAB-0280WJ)
This product is a human monoclonal antibody targets P. falciparum circumsporozoite protein (PfCSP). This antibody has been tested in vitro for their capacity to inhibit PfCSP traversal and invasion of a human hepatocyte cell line. This antibody can be used in applications, such as ELISA, WB, Neut.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 Binding values for the panel of IgG monoclonal antibodies to PfSPZs.
The values indicate the concentration of antibody required to reach a 10,000 MFI.
Tan, J., Sack, B. K., Oyen, D., Zenklusen, I., Piccoli, L., Barbieri, S., Foglierini, M., Fregni, C. S., Marcandalli, J., Jongo, S., Abdulla, S., Perez, L., Corradin, G., Varani, L., Sallusto, F., Sim, B., Hoffman, S. L., Kappe, S., Daubenberger, C., Wilson, I. A., … Lanzavecchia, A. (2018). A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nature medicine, 24(4), 401–407.
Specifications
- Immunogen
- Attenuated Plasmodium falciparum sporozoites (PfCSPs)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- P. falciparum circumsporozoite protein (PfCSP)
- Species Reactivity
- P. falciparum
- Clone
- MGU5
- Applications
- ELISA, WB, Neut
- Related Disease
- P. falciparum infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- P. falciparum circumsporozoite protein; PfCSP
- UniProt ID
- P02893
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
IgM Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-306 | Recombinant Human Anti-PfCSP Antibody (1210) | ELISA, Inhib | Human IgG |
| PABC-471 | Recombinant Human Anti-PfCSP Antibody (MGG4) | ELISA, FC | Human IgG1, κ |
| PABC-491 | Recombinant Human Anti-PfCSP Antibody (mab317) | ELISA, FuncS | Human IgG1, κ |
| PABC-492 | Human Anti-PfCSP Recombinant Antibody (PABC-492) | FuncS, SPR, ELISA, IF | Human IgG1, κ |
| VS-0723-CJ13 | Human Anti-PfCSP Recombinant Antibody (clone 663) | ELISA, IF, Inhib, Neut | Human IgG, κ |
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For Research Use Only. Not For Clinical Use.
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