AbPlus™ Anti-PGR Magnetic Beads (C262) (CAT#: VS-0424-XY212)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-PGR specific antibody (C262)

• Target
• PGR

• Immunogen
• Synthetic peptide of human progesterone receptor, ILAGMVKPLLFHKK (aa 919-933).

• Target Species
• Human, Mouse, Rat, Rabbit

• Antibody Clone
• C262

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

• Alternative Names
• Progesterone receptor Phospho S162; PR; NR3C3; progesterone receptor; nuclear receptor subfamily 3 group C member 3; PGR

• Gene ID
• 5241

• UniProt ID
• P06401

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