Recombinant Anti-PLA2 (AA 119-124 x AA 153-156) Biparatopic Antibody, Tandem scFv (Clone mAb2.23 x Clone mAb2.25) (CAT#: VS-0525-YC148)

This biparatopic antibody (bpAb) is designed to bind two distinct PLA2 epitopes. Its tandem scFv architecture involves the N-terminal fusion of the mAb2.23 scFv to the mAb2.25 scFv. Notably, Anti-PLA2 mAb 2.23 targets the linear epitope GPAENK (amino acids 119-124), while mAb 2.25 recognizes the minimal epitope PQFL (amino acids 153-156).

Specific Inquiry
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • Human PLA2
  • Species Reactivity
  • Human
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • mAb2.23
  • Clone 2
  • mAb2.25
  • Epitope 1
  • A linear epitope (bin 2) of GPAENK (aa 119-124)
  • Epitope 2
  • A minimal epitope (bin 1) of PQFL (aa 153-156)
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, Inhib
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Phospholipase A2

Target

  • Introduction
  • Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
  • Alternative Names
  • PLA2; Phospholipase A2; PLA2G1B; PLA2G2A; PLA2G2C; PLA2G2D; PLA2G2E; PLA2G2F

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