Recombinant Anti-PLA2 (AA 119-124 x AA 153-156) Biparatopic Antibody, Tandem scFv (Clone mAb2.23 x Clone mAb2.25) (CAT#: VS-0525-YC148)
This biparatopic antibody (bpAb) is designed to bind two distinct PLA2 epitopes. Its tandem scFv architecture involves the N-terminal fusion of the mAb2.23 scFv to the mAb2.25 scFv. Notably, Anti-PLA2 mAb 2.23 targets the linear epitope GPAENK (amino acids 119-124), while mAb 2.25 recognizes the minimal epitope PQFL (amino acids 153-156).
Specific Inquiry
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- Human PLA2
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- mAb2.23
- Clone 2
- mAb2.25
- Epitope 1
- A linear epitope (bin 2) of GPAENK (aa 119-124)
- Epitope 2
- A minimal epitope (bin 1) of PQFL (aa 153-156)
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, Inhib
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Phospholipase A2
Target
- Introduction
- Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
- Alternative Names
- PLA2; Phospholipase A2; PLA2G1B; PLA2G2A; PLA2G2C; PLA2G2D; PLA2G2E; PLA2G2F
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Human Antibody Products
IgG Antibody Products
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Fab Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1032CL | Anti-Human PLA2 Recombinant Antibody (mAb 1.18) | ELISA | Human antibody |
TAB-1033CL | Anti-Human PLA2 Recombinant Antibody (mAbs 2.4) | ELISA | Human antibody |
TAB-1032CL-S(P) | Anti-Human PLA2 Recombinant Antibody scFv Fragment (mAb 1.18) | ELISA | Human antibody |
TAB-1033CL-S(P) | Anti-Human PLA2 Recombinant Antibody scFv Fragment (mAbs 2.4) | ELISA | Human antibody |
TAB-1032CL-F(E) | Anti-Human PLA2 Recombinant Antibody Fab Fragment (mAb 1.18) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
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