Recombinant Anti-PLA2 (AA 119-124 x AA 153-156) Biparatopic Antibody, Tandem scFv (Clone mAb2.23 x Clone mAb2.25)

CAT#: VS-0525-YC148

This biparatopic antibody (bpAb) is designed to bind two distinct PLA2 epitopes. Its tandem scFv architecture involves the N-terminal fusion of the mAb2.23 scFv to the mAb2.25 scFv. Notably, Anti-PLA2 mAb 2.23 targets the linear epitope GPAENK (amino acids 119-124), while mAb 2.25 recognizes the minimal epitope PQFL (amino acids 153-156).

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • Human PLA2
  • Species Reactivity
  • Human
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • mAb2.23
  • Clone 2
  • mAb2.25
  • Epitope 1
  • A linear epitope (bin 2) of GPAENK (aa 119-124)
  • Epitope 2
  • A minimal epitope (bin 1) of PQFL (aa 153-156)
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, Inhib
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Phospholipase A2

Target

  • Introduction
  • Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
  • Alternative Names
  • PLA2; Phospholipase A2; PLA2G1B; PLA2G2A; PLA2G2C; PLA2G2D; PLA2G2E; PLA2G2F
REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS
Inquiry
Navs

Customer Review

Submit a review or a question

There are currently no Customer reviews or questions for VS-0525-YC148. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Article title:
DOI/PubMed URL:
Email:
Name:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "PLA2"

Select a product category from the dropdown menu below to view related products.

Specific Inquiry
Go to compare Add to compare

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare