Rabbit Anti-PLXNA1 Recombinant Antibody (clone R08-2J4) (CAT#: VS3-XY3468)

This product is a recombinant rabbit antibody targeting the human PLXNA1 (Plexin A1), which plays a role in axon guidance, invasive growth and cell migration. This antibody recognizes and binds to human PLXNA1. The antibody also has cross-reactivity against mouse or rat PLXNA1. It has been determined using Western Blot, Flow cytometry, Immunocytochemistry or Immunofluorescence.

Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat PLXNA1
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R08-2J4
  • Applications
  • WB, ICC, IF, FC
  • Related Disease
  • Dworschak-Punetha Neurodevelopmental Syndrome; Non-Specific Syndromic Intellectual Disability

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IF: 1/50-1/200
    FC: 1/50-1/100

Target

  • Alternative Names
  • NOV; NOVP; PLXN1; DWOPNED; PLEXIN-A1
  • Long Name
  • Plexin A1
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • Glycosylation at Asn77, Asn660, Asn672, Asn701, Thr726, Asn1043, Asn1187, and Asn1212 (NX_Q9UIW2 [NX_Q9UIW2-1])
    Ubiquitination at Lys1418 (NX_Q9UIW2 [NX_Q9UIW2-1])
    Modification sites at PhosphoSitePlus (Q9UIW2)
    Glycosylation from GlyGen (Q9UIW2) 10 sites, 2 O-linked glycans (2 sites)
  • Function
  • Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D.
    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.
    Plays a role in axon guidance, invasive growth and cell migration.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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